18例危重烧伤患者医院感染真菌回顾性分析  

Nosocomial fungal infections in 18 severely burn patients:an retrospective clinical analysis

作　　者：吴祖煌[1,2] 宋斌[1,2] 卓燕舞[3] 陈国养[1,2] 

机构地区：[1]解放军福州总医院第一附属医院烧伤整形科 [2]福建医科大学福总临床医学院,福建莆田351100 [3]莆田学院附属医院小儿科,福建莆田351100

出　　处：《中华医院感染学杂志》2011年第19期4025-4027,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析烧伤后真菌性感染的相关因素,进一步探讨真菌性医院感染的防治措施。方法回顾性分析2004年1月-2008年12月18例危重烧伤(烧伤面积≥30%体表总面积)后真菌性感染的病例资料。结果白色假丝酵母菌是危重烧伤真菌性医院感染的主要病原菌,占75.8%;长期使用广谱抗菌药物是最常见的诱因,烧伤程度重、住院时间长、低白蛋白血症、侵入性操作、高龄、大剂量激素的应用等也是该病重要的危险因素;临床表现无特异性,临床症状不典型。结论积极控制感染相关危险因素,合理使用抗菌药物,减少侵入性操作,提高患者机体免疫力和尽早切削痂治疗等是预防真菌性医院感染的主要措施。OBJECTIVE To analyze the predisposing factors and investigate the preventive measures for nosocomial fungal infection.METHODS The clinical features,therapy and outcome of 18 patients with in nosocomial fungal infection burn patients which happened from Jan 2004 to Dec 2008 were retrospectively reviewed.RESULTS Candida albican was the main pathogens causing nosocomial fungal infection.The rate of nosocomial fungal infection was higher in burn patients with long-term use of broad-spectrum antibiotic,severity of burn,long bed-days,hypoalbuminemia,invasive operation,long aging,abuse application of hormone.CONCLUSIONS We must take some measures to control the risk factors,reasonably use antibiotics,reduce the invasive procedure,improve physical immunity of the patients and perform crust treatment in early stage,which are key to prevention of nosocomial fungal infection.

关 键 词：烧伤 真菌 医院感染 预防治疗 

分 类 号：R181.32[医药卫生—流行病学]