ICU357株肺炎克雷伯菌的耐药性分析  

Drug resistance of 357 Klebsiella pneumobacillus strains isolated from ICU

作　　者：陈之力[1] 陈红辉[1] 李勇[1] 

机构地区：[1]温州市第二人民医院急救科,浙江温州325000

出　　处：《中华医院感染学杂志》2011年第19期4144-4145,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解重症监护病房(ICU)内肺炎克雷伯菌的耐药情况,为临床医师合理用药提供参考依据。方法从2008-2010年ICU送检的不同标本鉴定分离得到357株肺炎克雷伯菌,通过药敏试验获得肺炎克雷伯菌对12种抗菌药物的药敏率。结果肺炎克雷伯菌对12种抗菌药物的耐药率中阿米卡星和亚胺培南相对较低,耐药率分别为31.93%、30.25%,但总体耐药率较高。结论该研究中,阿米卡星和亚胺培南是控制该菌的相对有效药物;临床医师可根据耐药率,合理选择抗菌药物,控制耐药菌株的流行及医院感染,尤其是ICU内的菌株数量。OBJECTIVE To investigate the antibiotic resistance of Klebsiella pneumobacillus,and to provide reference to clinicist of using the medicine rationally.METHODS A total of 357 strains K.pneumobacillus from the different samples sent by ICU from 2008 to 2010 were isolated and identified.After the drug sensitive test,the drug resistance rate,intermediate rate and sensitivity rate of the bacteria to the twelve drugs were acquired.RESULTS Among the drug resistance rates,amikacin（31.93%） and imipenem（30.25%） were relatively low.But to the over trends,the drug resistance rates were still high.CONCLUSION In the study,amikacin and imipenem are the relatively effective drugs.The clinicians should control the strains,especially in the ICU.

关 键 词：重症监护病房 肺炎克雷伯菌 药敏试验 耐药率 

分 类 号：R378.996[医药卫生—病原生物学]