鲍氏不动杆菌的临床分布及耐药性分析  

Clinical distribution and drug resistance of Acinetobacter baumannii

作　　者：王日春[1] 许玲英[1] 方中飞 丁柳美[2] 

机构地区：[1]浙江省海盐县人民医院检验科,浙江海盐县314300 [2]复旦大学附属金山医院检验科,上海200540

出　　处：《中华医院感染学杂志》2011年第19期4146-4147,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解掌握鲍氏不动杆菌的临床分布及耐药性。方法收集2009年3月-2010年3月从医院分离的鲍氏不动杆菌菌株,采用VITEK-32型全自动细菌分析系统对菌株进行鉴定和药敏,并对结果进行分析。结果 137例菌株中,呼吸道标本占92.1%,ICU和内科占67.1%,鲍氏不动杆菌对头孢唑林、头孢西丁、头孢呋辛等第一、二代头孢以及氨苄西林耐药率较高,对亚胺培南、头孢哌酮/舒巴坦、阿米卡星霉素敏感性较好。结论多耐药菌株的出现应该引起临床的普遍关注和高度重视,并加强对抗菌药物使用的管理。OBJECTIVE To understand the drug resistance and the clinical distribution of the Acinetobacter baumannii.METHODS ABA strains were collected from Mar.2009 to Mar.2010,all strains were identificated with the VITEK-32 Automatic Bacterial Identification System.Minimum inhibitory concentrations（MICs） for organisms were determined by this System too.The results were evaluated based on Clinical and Labomtery Standards Institute（CLSI）.RESULTS Among those 137 strains,respiratory tract accounted for 92.1%,ICU and medical 67.1%.ABA haD high rate of drug resistance to cefazolin,cefoxitin,cephalosporin Fuxin and other first and second generation cephalosporins,while it was more sensitive to imipenem,cefoperazone/sulbactam,amikacin.CONCLUSION It should highly concentrate on the occurrence of multidrug-resistant strains and strengthen the management of using antibiotics.

关 键 词：鲍氏不动杆菌 临床分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]