肿瘤医院住院患者1316份标本的多药耐药菌感染分析  

Multidrug-resistant pathogens causing infections in 1316 specimens of inpatients in tumour hospital

作　　者：吴乾[1] 冯笑峰[2] 褚旭英[3] 

机构地区：[1]山西省肿瘤医院中医科,山西太原030013 [2]山西省肿瘤医院感染管理科,山西太原030013 [3]山西省肿瘤医院乳腺外科三病区,山西太原030013

出　　处：《中华医院感染学杂志》2011年第19期4163-4164,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解肿瘤医院感染病原菌分布及耐药性。方法对2008年11月-2009年4月医院送检标本中的病原菌检出及其多药耐药情况进行统计分析。结果 1316份送检标本中,有640份检出致病菌,检出率为48.6%;其中检出细菌者329份,占51.4%,检出真菌者205份,占32.0%,同时检出细菌和真菌者106份,占16.6%;在对检出细菌的435份样本中,发现多药耐药菌120株,主要为大肠埃希菌,占44.2%。结论肿瘤医院感染多药耐药病原菌以产β-内酰胺酶的大肠埃希菌为主,临床工作中要注意有针对性的选择对耐药菌株有效的抗菌药物。OBJECTIVE To study the distribution and multi-antimicrobial resistance of pathogens causing nosocomial infection（NI） in patients within Tumor Hospital.METHODS Pathogens were isolated from patient s in our hospital from Nov 2008 to Apr 2009 and the multi-animicrobial susceptibility was analyzed.RESULTS A total of 640 strains of pathogens were isolated from 1316 cases of NI,the isolation rate was 48.63%.Among these pathogens,there were 329 bacteria（51.4%）,205 fungi（32.0%） and 106 cases（16.6%）with both bacteria and fungi.120 MDR were isolated from the 435 cases of bacteria related pathogens.53 strains（44.2%） Escherichia coli were ESBLs producing strains.CONCLUSIONS The main pathogens causing NI in tumor hospital patients are ESBLs producing E.coli,MRSCNs,ESBLs-producing Klebsiella pneumoniae and also MRSA.Special attention and specific measures should be taken when treating these MDR infections in tumor hospital.

关 键 词：病原菌 耐药性 肿瘤 医院感染 

分 类 号：R378[医药卫生—病原生物学]