2008～2009年玉林市部分非淋球菌性尿道炎患者感染支原体检测及药敏分析  

Detection of Non-gonococcal Urethritis Patients Infected with Mycoplasma and Test of Drug Sensitivity in Yulin City,2008-2009

作　　者：林瑞玲[1] 全信斌[1] 叶瑞国[1] 

机构地区：[1]玉林市疾病预防控制中心,广西玉林537000

出　　处：《预防医学论坛》2011年第11期1001-1003,共3页Preventive Medicine Tribune

摘　　要：[目的]了解非淋球菌性尿道炎(NGU)患者的支原体感染及药敏情况,为临床正确用药提供参考。[方法]对2008～2009年到玉林市疾病预防控制中心诊治的1262例门诊疑为NGU患者进行支原体培养及药敏分析。采用支原体药敏试剂盒检测支原体,观察药敏结果。[结果]1262例NGU疑似患者标本中支原体培养阳性者532例,阳性率为42.16%。532例支原体阳性者中,单纯解脲支原体(Uu)感染371例,占69.74%;单纯人型支原体(Mh)感染25例,占4.70%;Uu+Mh混合感染136例,占25.56%。1262例患者中男性606例,女性656例,男女性支原体感染阳性率分别为26.24%、56.86%,差异有统计学意义(P<0.01)。单纯Uu感染者其药物敏感性最高的为交沙霉素(95.15%),其次为环脂红霉素(90.30%),耐药率最高为环丙沙星(64.15%);单纯Mh感染者其敏感性最高的为美满霉素(100.00%),其次为交沙霉素(80.00%),耐药率最高的为阿奇霉素,罗红霉素均为(84.00%);Uu+Mh混合感染者,敏感性最高的是交沙霉素(86.76%),其次为强力霉素(79.41%),耐药率最高的为环丙沙星(81.62%)。[结论]支原体感染以单纯Uu感染最为普通,临床应根据药敏结果合理选择抗生素,以有效控制泌尿生殖道支原体的感染。[Objective]To understand the mycoplasma infection and the drug sensitivity of non gonococcal urethritis patients and provide reference for correct clinical medication. [Methods]To observe the resuhs of drug sensitivity,mycoplasma was tested by a drug sensitivity kit.[Results]Of the 1 262 cases,532 were detected mycoplasma positive,with a positive rate of 12.16%,including 371 cases positive for Ureaplasma urealyticum （Uu） （69. 74%）,25 cases positive for Mycoplasma hominis （Mh） （1.70% ）,and 136 cases positive for two Ureaplasma mixed infection（25.56% ）. Of the 1 262 ca ses,606 cases were male patients and 656 cases were female patients.the difference in the positive rate between male and female patients had statistic significance（ P 〈0.01）. Uu was sensitive to Josamycin（95.15%）and Cycloate Erythromycin （90.30%）;Mh was sensitive to Minocycline（100.00%）and ,losamycin（80.00%）;the mixed infect ions of Uu＋ Mh was sensitive to Josamycin（86.76%）and Doxycycline（79. 11%）. Uu and Uu＋ Mh were most resistant to Ciprofloxacin （64. 15%）and Ciprofloxacin（81.62%）： Mh were both most resistant to Azithromycin （84.00%）and Roxithromycin （84.00%）. [Conclusion]Mycoplasma infection is dominated by Uu,and rational selection of antibiotics based on the results of drug sensitivity test will be important for effective control of mycoplasma infection in the urino-genital tracts.

关 键 词：支原体 药敏 耐药率 

分 类 号：R375[医药卫生—病原生物学]