新疆维吾尔族成年人颈动脉粥样硬化的患病率调查  

Prevalence and correlation factors of carotid atherosclerosis in Xinjiang Uygur adult population

作　　者：安尼瓦尔.阿不里孜 杨毅宁[1] 马依彤[1] 李晓梅[1] 袁山[1] 谢翔[1] 刘芬[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2011年第8期828-831,835,共5页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区重大科技专项课题(200733146-3)

摘　　要：目的调查新疆地区维吾尔族成年人颈动脉粥样硬化(CAS)的患病率及相关因素,为今后动脉粥样硬化的防治提供基础资料。方法四阶段整群随机抽样法,在新疆的7个地区抽取年龄在35岁以上维吾尔族样本4 352例,进行颈动脉超声及生化指标的测定,统计维吾尔族成年人CAS的患病率,并对CAS的相关因素进行Lo-gistic回归分析。结果新疆维吾尔族成年人CAS的患病率为30.9%,其中单纯颈动脉内膜中层厚度(IMT)增厚者占18.4%,非狭窄性斑块者占11.1%,狭窄性斑块者占1.4%。CAS发病的影响因素为男性、年龄、吸烟、高血压、糖尿病、代谢综合征、高TC血症、高TG血症、高尿酸血症。结论新疆维吾尔族成年人的CAS的患病率较高,男性、年龄、吸烟、高血压、糖尿病、代谢综合征、高TC血症、高TG血症及高尿酸血症等因素可能为新疆维吾尔族成年人CAS的独立危险因素。Objective To investigate prevalence and correlation factors of carotid atherosclerosis（CAS） in Xinjiang Uygur adult population,and it will provide the basic material for the prevention of atherosclerosis.MethodsFour-stage selected random samples age 35 and over were used to analyze the prevalence of CAS in Xinjiang Uygur adult population.Biochemical indicator were collected and the internal-media thickness（IMT） of carotid and the extent of plaque formation were evaluated by B-mode ultrasound.Logistic regression analysis was used to estimate the correlation factors of CAS.ResultsThe overall prevalence of carotid atherosclerosis in Xinjiang Uygur adult population was 30.9%.Increased thickness of IMT was found as 18.4%,with the prevalence rates of nonstenotic plaque and stenotic plaque were 11.1% and 1.4%,respectively.It was shown by logistic regression analysis that male,age,smoking,hypertension,diabetes mellitus,metabolic syndrome,hypercholesterolemia,hypertriglyceridemia and hyperuricemia were significantly associated with the severity of CAS.ConclusionThe prevalence of CAS in Xinjiang Uygur adult population was higher than those in ordmry people of the same age.Male,age,smoking,hypertension,diabetes mellitus,metabolic syndrome,hypercholesterolemia,hypertriglyceridemia and hyperuricemia maybe the independent risk factors related to CAS in Xinjiang Uygur adult population.

关 键 词：颈动脉粥样硬化 患病率 维吾尔族 流行病学研究 

分 类 号：R541.4[医药卫生—心血管疾病]