补肾益智颗粒剂提取工艺的研究  

Research on the Extraction Technology of Bushenyizhi Granules

作　　者：王玉璧[1] 王玉秀[1] 乔之龙[2] 张昱[2] 郭蕾[3] 

机构地区：[1]山西生物应用职业技术学院,山西太原030031 [2]山西中医学院第二中医院,山西太原030024 [3]山西中医学院,山西太原030024

出　　处：《中国中医急症》2011年第10期1606-1607,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：国家自然科学基金项目(30973700);山西省太原市科技项目民生科技计划项目(2010100342)

摘　　要：目的优选补肾益智颗粒最佳提取工艺。方法采用正交试验法,以出膏率、多糖含量为评价指标,考察加水量(A)、提取时间(B)和提取次数(C)对提取效果的影响。结果三个因素对提取效果均无显著性影响,其中C对提取效果的影响最大,各因素对提取效果影响顺序为C>A>B,其最佳提取工艺为:6倍量水,煎煮3次,每次煎煮0.5h。结论按确定的最佳提取工艺条件验证3次,其验证结果与正交试验结果一致,说明本提取工艺稳定可行。Objective：To screen out the best extraction condition of Bushenyizhi Granules.Methods：The amount of water（A）,the extraction time（B） and the extraction times（C） on the impact of the extraction effect were examined by the orthogonal design L9（34）.Results：3 factors were no significant impacts on the extraction.The C was the largest effect on the extraction.The order on the impact of the extraction was CAB.The optimum extraction process as follows：6 times the amount of water,boiling 3 times,each time boiling for 0.5 hours.Conclusion：According to the optimum extraction conditions to verify 3 times,the result shows that verification results are consistent with the orthogonal.This extraction process is stable.

关 键 词：补肾益智颗粒 提取工艺 正交设计 

分 类 号：R285.5[医药卫生—中药学]