四川省2009甲型H1N1流感的临床特点及预后分析  

Clinical characteristics and prognosis of influenza A pandemic(H1N1) cases in 2009 in Sichuan

作　　者：刘大凤[1] 张敏利[2] 徐蓉[1] 刘亚玲[1] 温贤敏[1] 曾义岚[1] 

机构地区：[1]成都市传染病医院国家中医药防治传染病重点研究室,四川成都610061 [2]成都中医药大学附属医院麻醉科,四川成都610041

出　　处：《临床肺科杂志》2011年第11期1657-1660,共4页Journal of Clinical Pulmonary Medicine

基　　金：四川省科技支撑计划项目(项目编号:2010SZ0014);四川省中医药管理局中医药科技专项课题(项目编号:2009A02)

摘　　要：目的分析四川地区甲型H1N1流感的临床特点及预后。方法分析我院2009年收治的271例甲型H1N1流感的临床特点及预后情况。结果 1、重症患者基础疾病少且轻,危重症患者基础疾病多且重;2、危重症组、重症组年龄较大、体温较高、病程较长;3、重症组1/3病例有脏器功能损害,危重症组超过1/2的病例有多器官功能损害;4、发热持续时间及症状持续时间均随病情加重而延长;5、轻症预后良好,重症总体预后好,危重症患者预后差。结论轻症及重症预后好;危重症预后差。Objective To analyze clinical characteristics and prognosis of 271 influenza A（H1N1） cases confirmed in Sichuan and provide reference for future controlling epidemic of new and outbreak infectious diseases.Methods To retrospectively analyze basal disease,clinical manifestation,laboratory test,treatment and prognosis of hospital admitted 271 cases of Influenza A（H1N1） in 2009.Results 1） The mild cases did not have basal disease.Cases with heavy clinical features had few and mild basal disease,such as hypertension and mild asthma.While cases in serious critical clinical features group had serious and multiply basal diseases,such as COPD and diabetes mellitus.2） Patients were older,temperature was higher,and the disease duration was longer along with the condition worsening.3） The clinical manifestation in mild clinical features group included fever,cough and pharyngalgia.Besides above,symptoms such as serious cough,expectorate,hemoptysis,chest pain,short of breath were common in the severe clinical features group and the serious critical clinical features group.Dyspnea and consciousness barrier were also common in the serious critical clinical features group.4） There was no organ dysfunction in mild clinical features group,of which 1/3 cases in the severe clinical features group had organ dysfunction and 1/2 case in the serious critical clinical features group had multi-organ function failure.5） GR%,TBIL,GLU,LDH and CRP were more obvious abnormal along with the condition worsening.6） The total heat duration（h）,the heat duration（h） after entering the group,the total symptom duration,the symptom duration after entering were longer along with the condition worsening.7） Prognosis in mild clinical features group was very good.Prognosis in the severe clinical features group was also good.But Prognosis in the serious critical clinical features group was the worst,especially cases with multi-organ function failure.Conclusions The mild A/H1N1 influenza is self-limiting disease,the symptom is mi

关 键 词：甲型H1N1流感 中医药治疗方案 比较分析 

分 类 号：R511.7[医药卫生—内科学]