生物可降解镁合金植入材料的医用特征  

Medical characteristics of degradable magnesium alloy as medical implant materials

作　　者：姜海英[1] 艾红军[2] 

机构地区：[1]大庆油田总医院口腔修复科,黑龙江省大庆市163001 [2]中国医科大学附属口腔医院口腔修复科,辽宁省沈阳市110002

出　　处：《中国组织工程研究与临床康复》2011年第34期6411-6415,共5页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：辽宁省自然科学技术基金(2008079):AZ31B可降解镁合金在颌骨组织工程中的应用研究~~

摘　　要：背景:镁及镁合金作为新型医用植入材料是近年来生物可降解材料的一个研究热点,其中合金化、生物相容性、表面改性涂层研究都有了很大进展。目的:对国内外镁及镁合金医用植入材料的研究现状及新进展作一综述。方法:应用计算机检索CNKI和Pubmed数据库中1998-01/2010-10关于镁及镁合金的文章,在标题和摘要中以"金属基生物材料;医用植入材料;镁合金;生物可降解;骨;生物相容性"或"metal matrix biomaterials;medical implant materials;magnesium alloy;biodegradable;bone;biocompatibility"为检索词进行检索。选择关于镁及镁合金的41篇文献进行综述。结果与结论:镁及镁合金作为新型医用植入材料,具有优异的力学性能和可降解性,正吸引着越来越多研究者的关注。但是由于镁及镁合金较差的耐蚀性能影响到临床上的应用。为了提高镁及镁合金耐蚀性能,研究者们对镁及镁合金进行了表面处理并取得重要进展,镁及镁合金必定会在医用金属植入材料领域得到广泛的应用。BACKGROUND：Magnesium and magnesium alloys as new medical implant materials are a hotspot of biodegradable materials in recent years,including alloying,biocompatibility,surface modification coatings,which have a great progress. OBJECTIVE：To summarize the present situation of domestic and international magnesium and magnesium alloy as medical implant materials. METHODS：A computer retrieval of CNKI and PubMed database 1998-01/2010-10 for articles about magnesium and magnesium alloy was conducted. In the title and abstract,＂metal matrix biological materials;medical implant materials;magnesium alloy;biodegradable;bone;biocompatibility＂ were used. Finally,41 articles were reviewed in this article. RESULTS AND CONCLUSION：Magnesium and magnesium alloys as new medical implant material with excellent mechanical properties and biodegradability are attracting more and more researchers＇ attention. But poor corrosion resistant performance of magnesium and magnesium alloy affects clinical applications. In order to improve the corrosion resistant performance,the researchers have performed magnesium and magnesium alloy surface treatment and made important progress. Magnesium and magnesium alloy are applied widely in biomedical metal implant material field.

关 键 词：金属基生物材料 医用植入材料 镁合金 生物可降解 骨 生物相容性 

分 类 号：R318[医药卫生—生物医学工程]