骨水泥材料在经皮椎体成形中的应用  

Application of bone cement in percutaneous vertebroplasty

作　　者：黄卫国[1] 易军飞[1] 白瑞飞[1] 刘友军[1] 陈通 

机构地区：[1]柳州市柳铁中心医院骨科,广西壮族自治区柳州市545007

出　　处：《中国组织工程研究与临床康复》2011年第34期6428-6431,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：背景:1987年首次报道经皮椎体成形应用于临床,目前该技术已广泛应用于治疗老年骨质疏松椎体压缩性骨折以及椎体肿瘤并取得良效,但仍有一些问题需关注和探讨。目的:对国内外骨水泥材料在经皮椎体成形中的临床应用进展进行综述,了解椎体成形的主要理论观点及存在的争议问题。方法:应用计算机检索2008-01/2011-01PubMed数据库相关文章,检索词为"vertebroplasty",并限定文章语言种类为English。同时计算机检索2006-01/2011-01CNKI数据库相关文章,检索词为"椎体成形",并限定文章语言种类为中文。共检索到文献725篇,最终纳入符合标准的文献28篇。结果与结论:经皮椎体成形应用于临床治疗老年骨质疏松椎体压缩性骨折以及椎体肿瘤取得良效,它既可以消除或缓解疼痛症状,又能够加固和强化椎体从而防止进一步塌陷。但如何选择病椎,单侧还是双侧穿刺,经皮椎体成形还是经皮椎体后凸成形,骨水泥的注入时机和注入量,如何避免穿刺损伤以及骨水泥的渗漏等仍需进一步研究。BACKGROUND：Percutaneous vertebroplasty（PVP） is firstly reported in clinical application in 1987 and it has been widely used and achieved good results in the treatment of senile osteoporotic vertebral compression fracture and vertebral tumor. However,some issues still need further study. OBJECTIVE：To summarize studies regarding the advanced clinical application of bone cement materials in PVP published both at home and abroad,and to understand the main theoretical perspectives and controversial issues about the vertebroplasty. METHODS：A computer-based online retrieval of PubMed database from January 2008 to January 2011 and CNKI database from January 2006 to January 2011 was performed,with the of vertebroplasty in English and in Chinese,and the language was limited of English and Chinese,respectively. A total of 725 documents were screened out and 28 of them were analyzed according to the inclusive criteria. RESULTS AND CONCLUSION：PVP has been proved to be effective for the treatment of senile osteoporotic vertebral compression fracture and vertebral tumors. PVP may eliminate or relieve pain symptoms,also enhance the vertebral body,thus preventing further collapse. However,some issues and technologies still need further exploration,for example,how to choose the fractured vertebrae？ Unilateral or bilateral pedicle puncture？ PVP or percutaneous kyphoplasty？ How to choose the injection timing and volume of bone cement？ How to avoid puncture damage and leakage of bone cement？

关 键 词：骨水泥 椎体成形 注入 经皮椎体后凸成形 综述文献 

分 类 号：R318[医药卫生—生物医学工程]