急性酒精中毒与颅脑损伤患者病情相关性分析  

The Correlation between Acute Alcoholism and Craniocerebral Injury

作　　者：林丰[1] 李思齐[1] 袁勇[1] 梁道明[1] 周东[1] 

机构地区：[1]昆明医学院第二附属医院急诊外科,云南昆明650101

出　　处：《昆明医学院学报》2011年第7期75-78,82,共5页Journal of Kunming Medical College

摘　　要：目的探讨急性酒精中毒对颅脑损伤患者病情的影响.方法回顾性分析我院2005年4月至2007年12月间收治的93例颅脑损伤患者的临床资料,按照是否饮酒随机分为观察组和对照组;比较两组患者入院时的一般情况和实验室指标、并发症和疗效.结果急性酒精中毒与入院血清白蛋白和血钙水平明显负相关(P<0.05);与入院ALT、AST、血糖、乳酸、胃肠功能障碍、入院血细胞比容、血肌酐、尿素氮以及缺氧呈正相关(P<0.05或P<0.01),与对照组相比,观察组患者治疗有效率(P<0.01)明显降低,并发症发生率明显升高(P<0.01).结论急性酒精中毒可进一步加重颅脑损伤.Objective To investigate the effect of acute alcoholism on the condition of patients with craniocerebral injury.Methods The clinical and laboratory data of 93 patients with craniocerebral injury treated in our hospital were analyzed retrospectively from Apr 2005 to Dec 2007.The patients were divided into two groups according to alcohol drinking or not.The general information and laboratory indexes on admission,complications and therapeutic effects of patients were compared between the two groups.Results Acute alcoholism was negatively correlated with the plasma levels of albumin and calcium（P0.05）,and positively correlated with alanine aminotransferase,aspartate aminotransferase,blood glucose,lactic acid,gastrointestinal dysfunction,hematocrit,serum creatinine,urea nitrogen and hypoxia（P0.05 or P0.01）.Compared with control group,the effective rate was decreased significantly（P0.01）,the incidence of complications was increased significantly in observation group（P0.01）.Conclusion Acute alcoholism can furtherly aggravate the craniocerebral injury.

关 键 词：急性酒精中毒 颅脑损伤 相关性 

分 类 号：R595.6[医药卫生—内科学] R651.1[医药卫生—临床医学]