米非司酮联合利凡诺在中期妊娠引产中的综合疗效分析  

Comprehensive Therapy of Mifepristone Combined with Rivanol for Minimum Abortifacient

作　　者：王旭颖[1] 

机构地区：[1]浙江省永康市妇幼保健院妇科,浙江永康321300

出　　处：《中国现代医生》2011年第27期87-88,90,共3页China Modern Doctor

摘　　要：目的探讨米非司酮联合利凡诺在中期妊娠引产中的临床效果。方法选取2009年3月～2011年3月来我院要求终止妊娠的妇女180例,按照随机数字表法分为联合组(给予米非司酮和利凡诺)、利凡诺组(单独给予利凡诺),观察两组孕妇的宫缩开始时间、引产时间、胎盘排出时间、引产痛、子宫出血量、宫颈撕裂及不良反应发生情况。结果联合组的宫缩开始时间、引产时间、胎盘排出时间均短于利凡诺组,差异具有统计学意义(P<0.05),联合组引产痛Ⅲ～Ⅳ级明显低于利凡诺组,差异具有统计学意义(P<0.05),两组产后2h的子宫出血量无显著性差异,但是宫颈撕裂、不良反应发生率差异有显著性(P<0.05)。结论米非司酮联合利凡诺用于中期妊娠引产中引产效果较好,能够在一定程度上弥补利凡诺单独应用的不足,提高引产成功率,是一种较为理想的中期妊娠引产方法。Objective To explore the clinical therapy of Mifepristone combined Rivanol for minimum abortifacient. Methods All 180 cases of pregnant women needing to terminate pregnancy from March 2009 to March 2010 in our hospital were divided into combination group （were given Mifepristone combined with Rivanol ）and Rivanol group （were given Rivanol ）randomly, to observe the time of uterine contraction beginning, total birth process, placenta removing time, induction of labor pain, postpartum hemorrhage, the laceration of cervix and adverse effect incidence in the two groups. Results The time of uterine contraction beginning, total birth process, placenta removing time in the combination group were shorter than those in the Rivanol group （P 〈 0.05 ）; induction of labor pain Ⅲ grade to Ⅳ grade in the combination group were much lower than those in the Rivanol group （P 〈 0.05 ）, there were no significant difference of postpartum hemorrhage between two groups, but with significant difference of the laceration of cervix and The adverse effects incidence （P 〈 0.05 ）. Conclusion Comprehensive therapy of Mifepristone combined with Rivanol for minimum abortifacient is good, this made up the defect of Rivanol to some extent. It can improve the success rate of labor induction and has proved that this is a proper method to minimum abortifacient.

关 键 词：米非司酮 利凡诺 中期妊娠引产 

分 类 号：R719.31[医药卫生—妇产科学]