酯交换法制备可生物降解脂肪族聚碳酸酯及其应用的研究进展  

Progress in Synthesis of Biodegradable Aliphatic Polycarbonate by Transesterification

作　　者：朱文祥[1] 李春成[1] 张栋[1] 肖耀南[1] 管国虎[1] 

机构地区：[1]中国科学院化学研究所工程塑料实验室,北京分子科学国家实验室,北京100190

出　　处：《高分子通报》2011年第10期79-85,共7页Polymer Bulletin

基　　金：中国科学院知识创新工程重要方向项目

摘　　要：脂肪族聚碳酸酯(APC)作为一类重要的可生物降解高分子材料,具有良好的生物降解性、生物相容性和物理机械性能,受到人们的广泛关注。APC的制备方法主要有光气法、开环聚合法、二氧化碳/环氧化物共聚法和酯交换法。近年来,有关开环聚合法和二氧化碳/环氧化物共聚法制备APC的研究越来越多,而酯交换法制备APC的研究相对较少。本文综述APC的合成方法和应用,并着重介绍酯交换法制备APC的研究进展。Aliphatic polycarbonates（APC）have attracted considerable attention as an important class of biodegradable polymers for their favorable biodegradability, biocompatibility and mechanical properties. APC are generally synthesized by the following four methods. （1）reaction of aliphatic diols with phosgene, （2） ring-opening polymerization of cyclic carbonates, （3） polymerization of epoxides with carbon dioxide,or（4）transesterification of dialkyl carbonates with aliphatic diols. Recently, there are lots of reports on synthesizing APC by methods（2）and（3）,while there are not so many reports on method （4）. This paper reviews the synthesis and application of APC,and the emphasis is placed on progress in synthesizing APC by transesterification.

关 键 词：脂肪族聚碳酸酯 生物降解 合成方法 酯交换法 

分 类 号：TQ323.41[化学工程—合成树脂塑料工业]