冠心病秽浊痰阻证FPA、TAFI水平与危险因素的相关性探讨  

Relationship between Coronary Heart Disease Turbid Phlegm Obstruction foul FPA,TAFI Levels and Risk Factors

作　　者：谢晓柳[1] 安冬青[1] 

机构地区：[1]新疆医科大学中医学院,新疆乌鲁木齐830000

出　　处：《辽宁中医杂志》2011年第10期1951-1953,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然基金项目(30760295)

摘　　要：目的观察冠心病秽浊痰阻证患者血浆纤维蛋白肽A(FPA)及凝血酶激活纤溶抑制物(TAFI)水平与危险因素的关系。方法:选取2010年1月-2010年7月新疆维吾尔自治区中医医院住院患者中冠心病秽浊痰阻证患者88例于清晨抽取空腹静脉血,进行血浆纤维蛋白肽A(FPA)及凝血酶激活纤溶抑制物(TAFI)的检测并观察其与冠心病各危险因素的相关性。结果:冠心病秽浊痰阻证血浆纤维蛋白肽A:吸烟史、高脂血症、高血压等危险因素的偏回归系数在0.05的概率水平具有统计学意义;冠心病秽浊痰阻证凝血酶激活纤溶抑制物:高脂血症、高血压、糖尿病的偏回归系数在0.05的概率水平具有统计学意义。结论:高血压及高脂血症对冠心病秽浊痰阻证血浆纤维蛋白肽A及凝血酶激活纤溶抑制物水平均具有影响,吸烟对冠心病秽浊痰阻证血浆纤维蛋白肽A水平具有显著影响,糖尿病对冠心病秽浊痰阻证凝血酶激活纤溶抑制物含量具有影响,冠心病秽浊痰阻证患者合并上述危险因素时血液黏滞程度更高,血栓形成风险更大。Objective：Turbid phlegm obstruction foul coronary heart disease patients with fibrinopeptide A（FPA） and thrombin activated fibrinolysis inhibitor（TAFI） levels and risk factors.Methods：January 2010-2010 Xinjiang Uygur Autonomous Region in July a total of 170 cases of hospitalized patients with Chinese medicine hospitals,foul turbid phlegm obstruction in patients with coronary heart disease 88 cases,in the early morning fasting venous blood,the plasma fibrinopeptide A（FPA） and thrombin activated fibrinolysis inhibitor（TAFI） with the detection and observation of the relationship between the risk factors with coronary heart disease.Results：Foul turbid phlegm obstruction coronary plasma fibrinopeptide A： smoking history,hyperlipidemia,hypertension and other risk factors for partial regression coefficients in the 0.05 probability level of statistical significance;coronary heart disease turbid phlegm obstruction foul coagulation enzyme activated fibrinolysis inhibitor： hyperlipidemia,hypertension,diabetes,partial regression coefficient of 0.05 was statistically significant probability level.Conclusion：Hypertension and hyperlipidemia turbid phle gm obstruction of coronary heart disease dirty Plasma fibrinopeptide A and thrombin activated fibrinolysis inhibitor levels were with the impact of smoking on coronary heart disease turbid phlegm obstruction foul plasma levels of fibrinopeptide A has a significant effect of diabetes on coronary heart disease turbid phlegm obstruction foul thrombin activated fibrinolysis inhibitor levels have an impact,coronary heart disease turbid phlegm obstruction foul of these risk factors in patients with a higher degree of blood viscosity,thrombosis at greater risk.

关 键 词：冠心病 秽浊痰阻证 血浆纤维蛋白肽A 凝血酶激活纤溶抑制物 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]