定量组织速度成像联合组织追踪成像评价川崎病患儿左心收缩功能  

Quantitative tissue velocity imaging combined with tissue tracking imaging for assessing left ventricular systolic function of children with Kawasaki disease

作　　者：翟秀全[1] 计晓娟[1] 余更生[1] 白永虹[1] 王荞[2] 唐毅[2] 郭军[1] 

机构地区：[1]重庆医科大学附属儿童医院心内科,重庆400014 [2]重庆医科大学附属儿童医院超声科,重庆400014

出　　处：《第三军医大学学报》2011年第19期2066-2069,共4页Journal of Third Military Medical University

基　　金：重庆市自然科学基金(2009BB5267)~~

摘　　要：目的联合应用定量组织速度成像(quantitative tissue velocity imaging,QTVI)及组织追踪成像(TissueTracking Imaging,TTI)评价急性期及慢性期川崎病患儿的左心纵轴收缩功能变化。方法选取我院2009年5月至2010年9月68例受试者纳入试验,年龄(5.94±3.02)岁。包括30例急性川崎病患者(急性期组),18例远期川崎病患儿(远期组),20例年龄匹配的健康儿童(对照组)。分别应用QTVI及TTI测量所有研究对象左室侧壁、下壁、前壁及后壁,室间隔前间隔及后间隔的最大纵向运动速度(peak systolic velocities,Vs)及最大位移(peak systolic velocities,Ds)。结果急性期组6个室壁的平均Vs在二尖瓣环段、基底段、中间段与对照组及远期组相比较差异显著(P<0.05),远期组的6个室壁的Vs在瓣环段、中间段显著低于对照组(P<0.05),在基底段与对照组相无差异(P<0.05)。急性期组6个室壁的平均Ds在二尖瓣环段、基底段、中间段与对照组和远期组比较差异显著(P<0.05),远期组的6个室壁的Ds在瓣环段、基底段显著低于对照组(P<0.05),在中间段与对照组无差异(P>0.05)。结论 QTVI联合TTI技术可用于检测川崎病急性期及远期患儿左室局部心肌收缩功能的降低。Objective To evaluate the left ventricular longitudinal systolic function of children with Kawasaki disease in acute and chronic phase by quantitative tissue velocity imaging（QTVI） and tissue tracking imaging（TTI）.Methods From April 2000 to September 2010,sixty-eight patients of our hospital were enrolled,whose average age was 5.94±3.02 years,including 30 patients with Kawasaki disease in acute phase（acute phase group）,18 patients with Kawasaki disease in chronic phase（chronic phase group） and 20 normal children（control group）.The peak systolic velocities（Vs） and peak systolic velocities（Ds） in lateral,inferior,anterior and posterior wall of left ventricle and in anteroseptal and posteroseptal wall of interventricular septum were measured using QTVI and TTI.Results The average Vs of the acute phase group was significantly lower than those of the chronic phase group and the control group in mitral annulus,basal and middle segments（P0.05）.The average Vs of the chronic phase group was significantly lower than that of the control group in mitral annulus and middle segments（P0.05）,but not in basal segment（P0.05）.The average Ds of the acute phase group was significantly lower than those of the chronic phase group and the control group in mitral annulus,basal and middle segments（P0.05）.The average Ds of the chronic phase group was significantly lower than that of the control group in mitral annulus and basal segments（P0.05）,but not in middle segment（P0.05）.Conclusion QTVI combined with TTI can be applied to detect dysfunction of regional left ventricular myocardium contraction in acute and chronic phase of Kawasaki disease.

关 键 词：川崎病 定量组织速度成像 组织追踪成像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R725.512[医药卫生—诊断学]