辅舒良在鼻内镜鼻窦手术围手术期的疗效观察  

Therapeutic efficacy of fluticasone propionate nasal spray in peri-operative endoscopic sinus surgery

作　　者：李晨[1] 黄建民[1] 

机构地区：[1]福建医科大学附属协和医院耳鼻咽喉科,福州350001

出　　处：《山东大学耳鼻喉眼学报》2011年第5期69-71,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的探讨辅舒良在鼻内镜鼻窦手术围手术期的辅助治疗效果。方法 将慢性鼻窦炎、鼻息肉病例随机分为对照组(96例)和观察组(94例)。对照组单纯给予常规抗生素、黏液溶解排除剂(吉诺通)等治疗;观察组在对照组的基础上,手术前后给予鼻腔局部皮质类固醇药物(辅舒良)治疗,比较两组疗效。结果观察组在术中出血量、术后术腔清洁时间、术后术腔上皮化时间及疗效方面都优于对照组,差异均有统计学意义(P<0.05)。结论辅舒良可以提高和巩固鼻内镜鼻窦手术的疗效。Objective To explore the therapeutic efficacy of fluticasone propionate nasal spray in peri-operative endoscopic sinus surgery.Methods Chronic rhinosinusitis and nasal polyp patients were randomly divided into the control group（96 cases） and the treatment group（94 cases）.The control group was routinely treated by antibiotic and mucus discharged drugs（gelomyrtol forte）.Besides routine treatment,topical corticosteroids application in the nasal cavity（fluticasone propionate nasal spray） was added in the treatment group.Results The results of operative bleeding duration,post-operative sinus clean duration,post-operative sinus epithelialize duration and therapeutic efficacy were in favor of the treatment group when compared with the control group（P0.05）.Conclusion Topical corticosteroids application in the nasal cavity（fluticasone propionate nasal spray） can improve and consolidate the therapeutic efficacy of endoscopic sinus surgery.

关 键 词：皮质类固醇 局部应用 鼻窦炎 慢性 治疗结果 

分 类 号：R765.41[医药卫生—耳鼻咽喉科]