应用实时三维心动图评价2型糖尿病患者左心室功能  

Clinical Research on Left Ventricular Function of Patients with Type 2 Diabetes Mellitus Evaluated by Real-time Three-diametional Echocardiography

作　　者：王志蕴[1,2] 张梅[1] 张运[1] 申洪明[2] 杨睿[1] 戴晓华[3] 陈良[1] 

机构地区：[1]教育部和卫生部心血管重构和功能研究重点实验室山东大学齐鲁医院心内科 [2]山东省医学科学院附属医院 [3]山东省立医院,山东省济南市250031

出　　处：《中国动脉硬化杂志》2011年第10期829-832,共4页Chinese Journal of Arteriosclerosis

基　　金：国家高技术研究发展计划863计划(2007AA02Z448);973计划(2006CB503803)资助

摘　　要：目的应用实时三维超声技术评价2型糖尿病患者左心室功能,探讨轴向运动指标早期评价糖尿病患者心功能减退的临床价值。方法选择已确诊的2型糖尿病患者36例,对照组25例健康者,进行了三维超声检查,定量分析室壁轴向运动的距离及所需时间,比较两组测量结果。结果糖尿病组左心室整体射血分数(EF)、局部射血分数(REF)与正常对照组比较差异均无统计学意义(P>0.05);而糖尿病组轴向运动平均距离的标准差(ESD)、最小距离(Em in)分别与正常对照组比较差异均具有统计学意义;糖尿病组平均距离所需时间占R-R间期平均百分比(E%)与正常对照组比较差异亦具有统计学意义(P<0.05)。结论应用轴向运动指标能够早期、无创准确测定2型糖尿病左心室轴向收缩功能减退,为早期干预,防治或延缓微血管病变、血管周边间质纤维化和糖尿病性心肌病的发生,提供更完整的定量信息。Aim To evaluate left ventricular function by the parameter of excursion of left ventricular wall motion in type 2 diabetes mellitus（T2DM） patients. Methods 36 T2DM patients and 25 normal subjects were investigated by real-time three-diametional echocardiography in order to quantitatively analyse the distance and time of the excursion,then the result of the two groups were compared. Results The regional ejection fractior（REF） and the whole ejection fraction（EF） of the two groups were not significantly different（P0.05）.Whole ejection fraction（EF） of the two groups were not significantly different（P0.05）.Compared with control group the standard difference（ESD） and minimum distance（Emin） of the excursion T2DM patients were decreased（P0.05）,and the time of excursion（E%） was increased in T2DM patients group（P0.05）. Conclusions The distance and time of excursion could be helpful for sensitively assessing the early left ventricular dysfunction and myocardiac damage and quantitatively provide accuracy information for clinical preventment and therapy of myocardiac damage in T2DM patients.

关 键 词：超声心动图 轴向运动指标 2型糖尿病 左心室功能 

分 类 号：R5[医药卫生—内科学]