皮质抑素的生物学效应  

Biological effects of cortistatin

作　　者：任雪平[1] 张霁[2] 

机构地区：[1]商丘师范学院生命科学系,河南商丘476000 [2]商丘职业技术学院教务处,河南商丘476100

出　　处：《商丘师范学院学报》2011年第9期97-99,共3页Journal of Shangqiu Normal University

摘　　要：皮质抑素是1996年发现的一种小分子的生物活性神经肽,是生长抑素家族的新成员,CST及其受体在人体多种组织中均有表达.CST与3种受体结合后能表现出多样的生物学效应:具有抑制运动、诱导睡眠、影响学习记忆等神经调节作用及一定的神经保护作用;并参与免疫系统和内分泌系统的调节,强效抑制炎症因子的表达,对缺血性损伤的心血管具有代偿性的保护作用.Cortistatin is a kind of biological activity neuropeptide of small molecule discovered in 1996 and a new member of somatostatin.CST and its receptors are expressed in many tissues of human body.The combination of CST and its receptors can produce various biological effects which can impede movement,induce sleep and protect nerves.They can also regulate immune system,intensify the expression of inflammatory cytokines and have compensating protective role for cardiovascular vessels caused by ischemia injury.

关 键 词：皮质抑素 神经肽 生物学效应 

分 类 号：R335[医药卫生—人体生理学]