血清视黄醇结合蛋白在肾病早期诊断中的应用  

Application of retinol binding protein on early diagnosis of nephrosis

作　　者：蒋最明 顾敏[1] 李仲余 

机构地区：[1]湖南省株洲市一医院检验科,412000

出　　处：《检验医学与临床》2011年第19期2344-2344,2346,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨血清视黄醇结合蛋白(RBP)在高血压肾病早期诊断中的应用价值。方法采用免疫透射比浊法和速率法检测65例肾病患者血清RBP、尿素(Urea)、肌酐(Cr),同时检测53例健康体检者作为对照。结果与对照组相比,肾病患者各组血清中RBP、Urea、Cr含量均有不同程度升高,其中RBP含量升高最为显著。结论血清RBP水平反映肾小球的滤过功能,可以作为肾病早期诊断的较敏感指标。Objective To evaluate the the value of retinol binding protein（RBP） on early diagnosis of hypertension-nephrosis.Methods The serum levels of RBP,urea and creatinine（Cr） from 65 patients（nephritic group） and 53 health examination person（control group） were detected.Results Compared with control group,all of RBP,urea and Cr levels increased in different extent,among the total,the level of RBP raised up obviously.Conclusion The level of RBP could respond the glomerular filtration rate in serum,and may be as a sensitive index on early diagnosis of hypertension-nephrosis.

关 键 词：视黄醇结合蛋白 尿素 肌酐 肾病 

分 类 号：R459.3[医药卫生—治疗学]