不同方法测定六味地黄丸(浓缩丸)中熊果酸含量的比较  

Comparison of Ursolic Acid Content in Liuwei Dihuang Pill(Concentrated Pill) Determined by Different Methods

作　　者：王世清 

机构地区：[1]濮阳市食品药品检验所,河南濮阳457000

出　　处：《中医学报》2011年第10期1215-1216,共2页Acta Chinese Medicine

摘　　要：目的:比较高效液相色谱法(HPLC)与薄层色谱扫描法(HPTLC)测定六味地黄丸(浓缩丸)中熊果酸含量结果的差别。方法:采用HPLC法、HPTLC法对六味地黄丸(浓缩丸)的同一供试品溶液进行熊果酸含量测定。结果:两种方法测得的结果基本接近。但HPTLC法的两份间偏差较大,且重复性较差。结论:HPLC法的精密度明显高于HPTLC法。Objective：To compare the difference of ursolic acid contents in liuwei dihuang Pill（concentrated pill） determined by high performance liquid chromatography（HPLC） and thin layer chromatography（TLC） scanning.Methods：HPLC and HPTLC were adopted to determine the content of ursolic acid in test sample solution of liuwei dihuang pill（concentrated pill）.Results：The results measured by two methods were almost approximate,but the deviation between two samples determined by HPTLC was larger and the repeatability was worse.Conclusion：The precision of HPLC is conspicuously higher than that of HPTLC.

关 键 词：六味地黄丸(浓缩丸) 熊果酸 高效液相色谱法 薄层色谱法 

分 类 号：R284.2[医药卫生—中药学]