2009年深圳口岸甲型H1N1流感疫情早期监测结果分析  

Analysis on monitoring results of influenza A(H1N1)in early stages of epidemic at Shenzhen ports

作　　者：刘胜牙[1] 朱玉兰[1] 李政良[1] 甄胜西[1] 黄彤文[1] 胡孔新[2] 叶健忠[1] 董瑞玲[1] 

机构地区：[1]深圳国际旅行卫生保健中心,广东深圳518033 [2]中国检验检疫科学研究院

出　　处：《中国国境卫生检疫杂志》2011年第5期300-302,321,共4页Chinese Journal of Frontier Health and Quarantine

基　　金：国家"十一五"重大科技专项基金(2009ZX10602-02);深圳出入境检验检疫局博士基金项目(SZ2010102)

摘　　要：目的分析2009年深圳口岸甲型H1N1流感疫情暴发早期监测的结果,阐明甲型H1N1病毒的传入特征。方法对深圳罗湖、福田地铁、深圳湾、皇岗、蛇口、文锦渡、大铲湾、机场、沙头角9个国境口岸出入境人员实行流感监测,对监测到的流感样病例采集咽拭子标本,并进行流行病学调查。运用WHO推荐的甲型H1N1实时荧光RT-PCR技术检测流感样病例的咽拭子标本。结果 2009年5月4日—2009年7月31日,深圳罗湖、福田地铁、深圳湾、皇岗、蛇口、文锦渡、大铲湾、机场、沙头角9个口岸监测到的流感样病例为2341份,其中,246份流感样病例的咽拭子标本中甲型流感病毒核酸检测阳性,检出率为10.51%;89份流感样病例的咽拭子标本中新型甲型H1N1流感病毒核酸检测阳性,检出率为3.80%。89份新型甲型H1N1流感病例中,男性54例,占60.67%,女性35例,占39.33%。早期病例年龄构成以50岁以下人群为主,其中,6～34岁人群最多,占总病例数的79.78%。89份甲型H1N1流感病例均为输入性病例。结论新型甲型H1N1流感疫情早期,深圳国境口岸监测到的输入性病例,从2009年5—7月,甲型流感病毒和新型甲型H1N1流感病例的检出率具有显著增加的趋势。Objective To analyze the monitoring results of influenza A （H1N1） in the early stages of epidemic among entry-exit personnel at Shenzhen ports, and to explore the infectious characteristics of influenza A （H1N1） virus. Methods The influenza surveillanee was implemented among entry-exit personnel from Luohu, Futian subway, Shenzhen wail, Huanggang, Shekou, Wengjindu, Dachanwan, Shenzhen Airport, and Shatoujiao Port. Throat swab from influcnza-like illness patients were collected and epidemiological investigation was carried out. Throat swab were detected influenza A （H1N1） by real-time RT-PCR that WHO recommended. Results A total of 2 341 samples of throat swabs from nine ports in Shenzhen from May 4 to July 31, 2009 were collected. A total of 246 cases were positive for influenza A virus nucleic acid detection and the positive rate was 10.51%. 89 specimens were identified as influenza A （H1N1） and the positive rate was 3.80%. Of these, 54 cases were male, accounting for 60.67%, 35 cases were female, accounting for 39.33%. Conclusion All of influenza A （H1N1） cases were imported cases at Shenzhen ports. The positive rate of influenza A viruses and influenza A （H1N1） is significantly increasing from May to July.

关 键 词：甲型H1N1流感 亚型病毒 实时荧光RT—PCR技术 国境 口岸 

分 类 号：R511.7[医药卫生—内科学]