我院2010年药品不良反应报告回顾性分析  

Retrospective analysis on adverse drug reactions in a Hospital of China in 2010

作　　者：赵晓娟[1] 姜鹏[1] 张少华[1] 

机构地区：[1]皖南医学院附属马鞍山市人民医院药事科,安徽马鞍山243000

出　　处：《安徽医药》2011年第11期1450-1453,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的了解该院药品不良反应(ADR)发生的特点及规律,促进临床合理用药。方法对该院2010年收集到的1 031例ADR报告进行统计分析。结果 ADR的发生率男性与女性之比为1.01∶1,多发于60岁以上人群,以住院患者多见,发生级别以一般不良反应为主,给药途径以静脉滴注为主。抗感染药物占50.53%,主要为喹诺酮类和头孢菌素类。ADR临床表现以皮肤及附件损害和消化系统损害为主。ADR转归中,好转占89.04%。结论临床应重视抗菌药物和中药注射剂的合理使用,加强ADR监测,减少或避免ADR的发生。Aim To probe into the characteristics and regularity of adverse drug reactions（ADR） in our hospital and to promote clinical use of drugs.Methods 1031 ADR cases reported in our hospital in 2010 were collected and analyzed statistically.Results Of the 1 031 ADR cases,the ratio of male to female was 1.01：1.37.34% of the cases were collected from patients over the age of 60 and most were general in hospital induced by intravenous administration.50.53% of the cases were associated with anti-infective agents,among which 35.27% by quinolones and 32.17% by cephalosporins.The ADR cases were chiefly manifested as lesion of skin and its appendants and digestive system injury.89.04% of the symptom improved.Conclusion Creat attention should be paid to rational use of antibiotics and traditional Chinese medicine preparations.ADR monitoring should be strengthened to reduce or avoid the incidence of ADR.

关 键 词：药品不良反应 报告 分析 

分 类 号：R97[医药卫生—药品]