妊娠期糖尿病合并妊娠肝内胆汁淤积症对围产儿的影响  

The effects to the perinatal outcome in gestational diabetes mellitus complicated with intrahepatic cholestasis of pregnancy

作　　者：李艳 徐曦[2] 周淑[3] 刘毅 高岚 付利侠 

机构地区：[1]成都市妇女儿童中心医院妇产科,四川成都610091 [2]眉山市人民医院妇产科,四川眉山620000 [3]四川大学华西第二医院妇产科,四川成都610041

出　　处：《四川医学》2011年第9期1357-1359,共3页Sichuan Medical Journal

摘　　要：目的探讨妊娠期糖尿病合并妊娠肝内胆汁淤积症对围产儿结局的影响。方法回顾性分析我院2008年1月～2010年10月住院分娩的妊娠期糖尿病合并妊娠期肝内胆汁淤积症(GDM+ICP组)孕妇180例临床资料,与同期住院的妊娠期糖尿病(GDM组)426例、妊娠期肝内胆汁淤积症(ICP组)474例孕妇所分娩围产儿的结局情况分别进行比较。结果 GDM+ICP组34周前终止妊娠率、新生儿窒息率、Ⅱ度以上羊水粪染率、小于胎龄儿发生率显著高于其余两组(P<0.05)。结论妊娠期糖尿病合并妊娠肝内胆汁淤积症围产儿不良结局风险增加,应加强胎儿监护,适时终止妊娠,提高出生质量。Objective To explore the effects on the perinatal outcome in gestational diabetes mellitus（GDM） complicated with intrahepatic cholestasis of pregnancy（ICP）.Methods Collect the clinical datum of 1080 pregnant women of the last three year,dividing into three groups： Group GDM and ICP 180,Group GDM 426 and Group ICP 474,and analying the perinatal outcome between group GDM and ICP and group GDM,between group GDM and ICP and group ICP.Results The rate of terminating pregnancy less than 34 gestational weeks（9.44%）﹑the rate of neonatal asphyxia（7.22%） ﹑the rate of amniotic fluid pollution over than Ⅱ（21.11%）﹑the rate of small for gestational age（7.22%） of Group GDM and ICP was higher than group GDM and group ICP,And there is significantly difference（P0.05） among these three groups.Conclusion The risk of adverse perinatal outcome was added in gestational diabetes mellitus complicated with intrahepatic cholestasis of pregnancy.Inorder to Improving the perinatal outcome,enhancing fetal monitoring and termination of pregnancy in suitable time is very important.

关 键 词：妊娠期糖尿病 妊娠肝内胆汁淤积症 围产儿结局 

分 类 号：R714.25[医药卫生—妇产科学]