Catalyst-free Multicomponent Synthesis of β-Mercapto Diketones in Water  

作　　者：Li, Li Liu, Bokai WU, Qi Lin, Xianfu 

机构地区：[1]Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang 310027, China

出　　处：《Chinese Journal of Chemistry》2011年第9期1856-1862,共7页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foun-dation of China （Nos. 20704037, 20872130 and 20874086） and the Zhejiang Provincial Natural Science Foundation （Nos. 2008-Y407086, 2009-Y4080198 and 2010-Z4090225）.

摘　　要：A simple, efficient and eco-friendly route has been developed for the synthesis of fl-mercapto diketones via a multicomponent reaction of an aldehyde, acetylacetone and thiol in water. This methodology affords a number of β-mercapto diketone derivatives in moderate to good yields.A simple, efficient and eco-friendly route has been developed for the synthesis of fl-mercapto diketones via a multicomponent reaction of an aldehyde, acetylacetone and thiol in water. This methodology affords a number of β-mercapto diketone derivatives in moderate to good yields.

关 键 词：CATALYST-FREE multicomponent reaction β-mercapto diketone water chemistry THIOL 

分 类 号：O657.3[理学—分析化学] TB333[理学—化学]