Synthesis of New 2-Phenylpyrano[3,2-b]phenothiazin- 4（6H）-one Derivatives  

作　　者：Bansode, Tanaji N. Meshram, Gangadhar A.t 

机构地区：[1]Department of Chemistry, B. N. N. College, Bhiwandi, Thane （M.S.） 421 305, India [2]Oepartment of Chemistry, University of Mumbai, Santacruz （East）, Mumbai 400 098, India

出　　处：《Chinese Journal of Chemistry》2011年第9期1917-1921,共5页中国化学（英文版）

摘　　要：A new synthesis of 2-phenylpyrano[3,2-b]phenothiazin-4（6H）-one derivatives was reported. First 2,10-diacetyl-3-hydroxyphenothiazine （2） was converted into their benzoyloxy esters （3a--3j） using different aro- matic carboxylic acids in the presence of phosphorous oxychloride in pyridine. Benzoyloxy esters were converted into their 1,3-diones （4a--4j） by using dry KOH in pyridine via Baker-Venkataraman transformation reaction. The 1,3-diones thus obtained were cyclised to pyranophenothiazines （Sa--Sj） by refluxing in an acetic acid/HCl mixture.A new synthesis of 2-phenylpyrano[3,2-b]phenothiazin-4（6H）-one derivatives was reported. First 2,10-diacetyl-3-hydroxyphenothiazine （2） was converted into their benzoyloxy esters （3a--3j） using different aro- matic carboxylic acids in the presence of phosphorous oxychloride in pyridine. Benzoyloxy esters were converted into their 1,3-diones （4a--4j） by using dry KOH in pyridine via Baker-Venkataraman transformation reaction. The 1,3-diones thus obtained were cyclised to pyranophenothiazines （Sa--Sj） by refluxing in an acetic acid/HCl mixture.

关 键 词：acetyl phenothiazine Baker-Venkataraman transformation 1 3-diones pyranones pyranophenoth-iazine 

分 类 号：TQ455.47[化学工程—农药化工] O626.12[理学—有机化学]