3种镇痛方法在人工流产手术中应用的效果观察  

作　　者：朱琼芳[1] 陈旭素[1] 房洁瑜[1] 李芳[1] 

机构地区：[1]中山大学附属第一医院麻醉科恢复室,广东广州510080

出　　处：《现代临床护理》2011年第9期41-42,共2页Modern Clinical Nursing

摘　　要：目的探讨芬太尼、瑞芬太尼和舒芬太尼联合异丙酚在人工流产手术中的应用效果。方法选择妊娠6-12周的患者240例,根据采用镇痛方法不同分为芬太尼联合异丙酚组(芬太尼组)、瑞芬太尼联合异丙酚组(瑞芬太尼组)、舒芬太尼联合异丙酚组(舒芬太尼组),每组各80例。比较3种镇痛方法的效果。结果 3组患者的手术时间和宫颈松弛度良好率比较,差异无统计学意义(均P>0.05)。3组患者呼吸抑制、镇痛效果和术后唤醒时间比较,差异具有统计学意义(均P<0.05)。舒芬太尼组呼吸抑制发生率较瑞芬太尼组和芬太尼组高;舒芬太尼组镇痛效果优于瑞芬太尼组和芬太尼组;舒芬太尼组术后唤醒时间较瑞芬太尼组和芬太尼组长。结论芬太尼或瑞芬太尼比舒芬太尼联合异丙酚更适合作为人工流产的镇痛药物,具有安全和有效性。做好呼吸和循环监测及腹痛护理对提高手术效果具有积极的意义。Objective To compare the effects of fentanyl,remifentanil and sulfentanyl on induced abortion. Methods 240 pregnant women with pregnancy of 6-12 weeks were selected and divided in equal number into three groups（F,R and S） . The three groups were anesthetized with fentanyl,remifentanil and sulfentanyl,respectively. Results There were no significant differences between the groups in respect of operation duration and laxitas of cervix（all,P 0.05） . As for analgesia effect and time for awakening them,F group had a higher incidence of respiratory depression than the other two groups;S group was better in analgesia effect than other two groups and S group had a longer time for awakening than the other two groups. Conclusions Fentanyl and remifentanil are more effective and safer than sulfentanyl for the analgesia during induced abortion. Better performances of respiratory and circulation monitoring and nursing of abdominal pains are good for the ensured therapeutic effects.

关 键 词：人工流产 芬太尼 瑞芬太尼 舒芬太尼 镇痛 宫颈松弛度 呼吸抑制 

分 类 号：R614[医药卫生—麻醉学]