多种干预措施对呼吸机相关性肺炎发生的影响  

Impact of multiple intervention measures on ventilator-associated pneumonia

作　　者：蒲丹[1] 张卫东[1] 谭成[1] 宗志勇[1] 舒明蓉[1] 刘葆华[1] 杨宝玉[1] 乔甫[1] 

机构地区：[1]四川大学华西医院感染管理科,四川成都610041

出　　处：《中华医院感染学杂志》2011年第20期4211-4213,共3页Chinese Journal of Nosocomiology

摘　　要：目的评价实施多种干预策略对呼吸机相关性肺炎(VAP)发生的影响。方法于2010年9月-2011年3月综合ICU共纳入监测对象1017例;前瞻性地调查实施干预措施前VAP发生率等资料,与干预后VAP的发生率等进行比较。结果干预前后2组患者在年龄、性别、入院时的情况、死亡率等资料差异无统计学意义;干预后的患者APACHEⅡ评分低于干预前患者(P<0.05);干预前VAP感染率为37.74‰,干预后为22.60‰,差异有统计学意义(P<0.05,OR=0.61)。结论实施多种简单、易行的干预措施对预防VAP的发生具有重要意义。OBJECTIVE To assess the impact of the combined interventions to improve respiratory infection control practices in ventilator-associated pneumonia（VAP） rates in ICUs.METHODS A total of 1017 cases in comprehensive ICU from Sep 2010 to Mar 2011 were monitored;The clinical data,such as the incidence of VAP before implementing the intervention measures were prospectively investigated,which were compared with that after implementing intervention measures.RESULTS Patients assessed during preintervention were similar to patients assessed during prointervention with age,sex,type of admission and mortality.Patients who were admitted during preintervention had significantly lower APACHE scores than patients admitted during preintervention（P〈0.05）;the infection rate of VAP before intervention was 37.74‰,and that after the intervention was 22.60‰,the difference was statistically significant（P〈0.05,OR=0.61）.CONCLUSION To implement multiple simple and feasible intervention measures has great significance in preventing VAP.

关 键 词：呼吸机相关肺炎 重症监护病房 干预 

分 类 号：R181.32[医药卫生—流行病学]