HPLC法测定枳壳饮片中辛弗林的含量  

Determination of synephrine in Fructus Aurantii and its processed products by HPLC

作　　者：蒋以号[1] 曹旻旻 龚千锋[3] 

机构地区：[1]南昌大学环境与化学工程学院,南昌330031 [2]康美药业股份有限公司,普宁515341 [3]江西中医学院,南昌330004

出　　处：《中华中医药杂志》2011年第10期2363-2364,共2页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：江西省科技厅重大项目(赣科发计字[2007]189号)~~

摘　　要：目的:对枳壳生品及不同炮制品中辛弗林的含量进行考察。方法:色谱柱为E1823028 C18柱(250mm×4.6mm,5μm);流动相:甲醇-0.01mol/L盐酸(52:48),柱温30℃,流速1.0mL/min,检测波长285nm。结果:樟帮炮制品中的辛弗林含量低于药典法炮制品。结论:枳壳不同炮制品的内在质量有明显差异。Objective： To explore the contents of synephrine in Fructus Aurantii and its processed products.Methods： The chromatographic conditions were as follows： E1823028 C18 Column（250mm×4.6mm,5μm）,mobile phase of methanol-0.01%chlorhydric acid（volume ratio of 52：48）,the column temperature at 30℃,flow phase rate being 1.0mL/min and detection wavelength at 285nm.Results： Synephrine contents of the product processed by Zhang-Bang method were lower than that of by Pharmacopoeia method.Conclusion： There is a significant difference in intrinsic quality among various processed products of Fructus Aurantii.

关 键 词：枳壳 辛弗林 含量测定 高效液相色谱 

分 类 号：R286.0[医药卫生—中药学]