B型利钠钛在鉴别慢性阻塞性肺疾病和慢性心力衰竭中的价值  

Value of B-natriuretic peptide in differentiating COPD and heart failure

作　　者：李勇[1] 郭翔云[1] 康国平[1] 朱宇[2] 刘春燕[2] 

机构地区：[1]四川省巴中市中心医院急诊科,636000 [2]四川省巴中市中心医院呼吸内科,636000

出　　处：《中国现代医药杂志》2011年第10期59-60,共2页Modern Medicine Journal of China

摘　　要：目的探讨B型利钠钛(BNP)对慢性阻塞性肺疾病(COPD)和慢性心力衰竭(CHF)鉴别诊断的价值。方法选择我院COPD急性加重期、COPD稳定期和慢性心力衰竭患者各30例,测定其血清BNP含量,比较几组患者血清BNP水平的高低。结果慢性心力衰竭组血清BNP水平显著高于COPD稳定期和COPD急性加重期组(P<0.01);COPD急性加重期组血清BNP水平显著高于COPD稳定期(P<0.01)。结论 BNP可作为辅助诊断慢性心力衰竭的敏感指标,也对COPD急性加重的诊断有参考价值。Objective To assess the value of BNP in differentiating COPD and heart failure. Methods We recruited 30 patients with stable COPD, 30 with COPD exacerbation and 30 with chronic heart failure. B-natriuretic peptide levels were obtained in the 90 patients. Results B-natriuretic peptide level was significantly higher in the chronic heart failure group than the stable COPD group and the COPD exacerbation group（P〈0.01）. BNP levels of patients with COPD exacerbation were significantly higher than the group of patients with stable COPD （P〈0.01）. Conclusion BNP can be not only sensitive index of CHF＇s auxiliary diagnosis, but reference of acute exacerbation of COPD.

关 键 词：B型利钠肽 慢性阻塞性肺疾病 慢性心力衰竭 

分 类 号：R541.6[医药卫生—心血管疾病] R563.9[医药卫生—内科学]