医用近β型TLM合金的超亲水表面改性  

Superhydrophilic Surface Modification of Medical Near β-Type Titanium Alloy TLM

作　　者：李慧颖[1] 吴锋[1] 邵茜[1] 付涛[1,2] 孙传铸[1] 吴晓明[1] 

机构地区：[1]西安交通大学生命科学与技术学院,陕西西安710049 [2]燕山大学,河北秦皇岛066004

出　　处：《钛工业进展》2011年第5期23-26,共4页Titanium Industry Progress

基　　金：陕西省科技计划项目(2007K06-08);亚稳材料制备技术与科学国家重点实验室(燕山大学)开放课题(201107)

摘　　要：医用近β型钛合金TLM(Ti-25Nb-3Zr-2Sn-3Mo)具有优良的力学和生物学性能。TLM合金经过NaOH溶液处理后表面形成了钛(铌)酸钠凝胶层,再经过稀HCl浸泡后转化为氧化钛(铌)凝胶层。经过2.5 mol/L NaOH(12 h)-HCl处理的TLM合金表面形成了纳米多孔凝胶层,15 min紫外照射处理后达到超亲水(接触角<5°)。血液相容性实验表明,超亲水TLM合金试样表面黏附的血小板数量少于磨光TLM试样。因此,超亲水表面改善了TLM合金的血液相容性。Medical nearβ-type titanium alloy of TLM （Ti-25Nb-3Zr-2Sn-3Mo） has good mechanical and biological properties. When TLM alloy is subjected to the NaOH solution treatment, sodium titanate （niobate） gel layer will be formed on the surface, and the gel layer will be converted into titania （niobium oxide） gel layer after the dilute HC1 treatment. The TLM sample with 2.5 mol/L NaOH（ 12 h）-HC1 treatment has nano porous gel layer, and becomes superhydrophilic （contact angle 〈 5°） after UV irradiation treatment for 15 min. The blood compatibility tests show that the superhydrophilie TLM sample has less platelet adhesion on the surface than the ground TLM sample. Thus, the superhydrophilic surface has improved blood compatibility of the TLM alloy.

关 键 词：医用钛合金 TLM表面改性 血液相容性 亲水性 

分 类 号：R318.08[医药卫生—生物医学工程]