丝素蛋白性状对磷酸钙骨水泥性能的影响  

Effects of character of silk fibroin on properties of calcium phosphate cement

作　　者：谢瑞娟[1,2] 万琼[2] 于法鹏[2] 黄阳阳[2] 

机构地区：[1]苏州大学现代丝绸国家工程实验室,江苏苏州215123 [2]苏州大学纺织与服装工程学院,江苏苏州215006

出　　处：《纺织学报》2011年第10期1-5,共5页Journal of Textile Research

基　　金：江苏省高校省级重点实验室开放课题(KJS1014);江苏高校优势学科建设工程资助项目(苏政办发〔2011〕6号);卫生公益性行业科研专项经费项目(200802152)

摘　　要：在磷酸钙骨水泥(CPC)中加入不同性状丝素蛋白可改善其力学性能,为此,用X射线衍射、红外光谱研究材料的结构,用扫描电子显微镜观察材料的表面形态,用排液法测定材料的孔隙率,用通用力学试验机测定样品的力学性能。结果表明:在CPC中加入不同性状丝素蛋白的固化反应产物与纯CPC相似,均出现了羟基磷灰石(HA);不同性状丝素蛋白均能明显提高CPC的弯曲强度;丝素蛋白性状对CPC的弯曲断裂功影响明显;含有丝素纤维的弯曲断裂功增加明显,是纯CPC的7～21.8倍;加入丝素蛋白对材料的结构无明显影响,但材料的孔隙率有所下降。The mechanical properties of calcium phosphate cement（CPC） were improved by adding silk fibroin with different characters.The structure of the resulted product was investigated by X-ray diffraction and Fourier transform infrared spectroscopy.Its surface morphology was observed by scanning electron microscopy.The porosity of the product was measured by drainage method and the mechanical properties were tested by instron universal testing machine.The results showed that the products of hardening reaction of CPC containing silk fibroin were similar to that of pure CPC,and hydroxyapatite produced in both reactions.Silk fibroin with different character significantly improved the flexural strength of CPC.The character of the silk fibroin had distinct effects on the work-of-fracture,and the work-of-fracture of CPC by silk fibers increased significantly,which was 7-21.8 times of that of pure CPC.The character of the silk fibroin had no significant effects on the structure,but the porosity slightly decreased.

关 键 词：磷酸钙骨水泥 丝素 弯曲强度 结构 

分 类 号：R318[医药卫生—生物医学工程]