菊叶三七生物碱成分的研究  

STUDIES ON THE ALKALOIDS OF GYNURA SEGETUM (LOUR.) MERR.

作　　者：袁珊琴[1] 顾国明[1] 魏同泰 

机构地区：[1]军事医学科学院,北京100850

出　　处：《药学学报》1990年第3期191-197,共7页Acta Pharmaceutica Sinica

摘　　要：从菊科蒂叶三七植物中分离出六个生物碱,对其中四个进行了鉴定。光谱数据证明:生物碱Ⅰ和Ⅱ分别为已知的千里光碱(senecionine,Ⅰ)和千里光菲灵碱(seneciphylline,Ⅱ),生物碱Ⅲ和Ⅳ为新成分,分别命名为菊三七碱甲(sineciphyllinine,Ⅲ)和菊三七碱乙[(E)-seneciphylline,Ⅳ]。Six alkaloids were isolated from Gynura segetum (Lour.) Merr. Four of them were identified. Alkaloids Ⅰ and Ⅱ were identified as known senecionine and seneciphylline, respectively, Alkaloids Ⅲ and Ⅳ were found to be new compounds named seneciphyllinine and (E)-seneciphylline respectively Their structures were confirmed on the basis of spectral data (UV, IR, MS, ~1 HNMR,^(13)CNMR, C-H COSY).

关 键 词：菊叶三七 菊三七碱 成分 

分 类 号：R284.2[医药卫生—中药学]