滇黄芩中滇黄芩新素的结构研究  

STUDIES ON THE STRUCTURE OF SCUTEAMOENIN FROM THE ROOT OF SCUTELLARIA AMOENA

作　　者：胡碧煌[1] 刘永漋 章天 宋万志[3] 

机构地区：[1]中国医学科学院药用植物资源开发研究所,北京100094 [2]京华医科大学中药专业1988届 [3]中国医学科学院药物研究所北京,100050

出　　处：《药学学报》1990年第4期302-306,共5页Acta Pharmaceutica Sinica

摘　　要：前已报道自四川产滇黄芩Scutellaria,amoena C.H.Wright中分离出五种黄酮成分和从云南产的中得到另八个黄酮类化合物。本文继续报道从云南产滇黄芩中得到的六个化合物和从四川产本种植物中得到一个黄酮化合物的结构鉴定。In continuing our studies on the flavonoids from Scutellaria amoena G.H.Wright, a new flavanone (Ⅰ)and six known compounds (Ⅱ～Ⅶ) were isolated from the roots of this plant. On the basis of spectroscopic analysis (UV,~1H NMR, ^(13)C NMR, MS and CD) and chemical evidence, the structure of the new compound was elucidated as (2S)-2',5,6'-trihydroxy-7-methoxyflavanone (Ⅰ) and named scuteamoenin, the other six known compounds were identified as (2R,3R)-3,5,7-trihydroxyflavanone (Ⅱ), 2',3,5,6',7-pentahydroxyflavone (Ⅲ), 2',5,7_trihydroxy_6_methoxyflavone (Ⅳ), skullcaflavone Ⅱ (Ⅴ) , chrysin (Ⅵ) and β-sitosterol (Ⅶ) respectively. Compounds Ⅱ-Ⅶ were obtained from this plant for the first time.

关 键 词：滇黄芩 滇黄芩新素 黄酮类 

分 类 号：R284.1[医药卫生—中药学]