蒙古黄芪化学成分的分离鉴定  

ISOLATION AND IDENTIFICATION OF CHEMICAL CONSTITUENTS OF ASTRAGALUS ROOT

作　　者：贺正全[1] 王宝琹[1] 

机构地区：[1]中国药品生物制品检定所,北京100050

出　　处：《药学学报》1990年第9期694-698,共5页Acta Pharmaceutica Sinica

摘　　要：从蒙古黄芪(Astragalus membranaceus Bge.var.mongholicus(Bge.)Hsiao)乙醇提取物中分离得到10个单体,分别鉴定为棕榈酸(Ⅰ),羽扇醇(Ⅱ),β-谷留醇(Ⅲ),黄芪皂甙Ⅳ(astragaloside Ⅳ,Ⅳ),黄芪异黄烷甙(3S-(—)mucronulatol-7-D-glucopyranoside,Ⅴ),胡萝卜甙(Ⅳ),α-联苯双酯(dimethyl 4,4-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2-dicarboxylate,(Ⅶ),天冬酰胺(Ⅷ),γ-氨基丁酸(Ⅸ),蔗糖(Ⅹ)。其中Ⅰ,Ⅱ和Ⅸ首次由蒙古黄芪巾分得,联苯双酯(Ⅶ)为已知合成物,但在天然药物黄芪中属首次分出,黄芪异黄烷甙(Ⅴ)未见报道。Ten constituents have been isolated from the alcoholic extract of Astragalus membranaceus var. monghlicum root. All of them were identified. Armong them astraisoflavanin (3S-(-)-mucronulatol-7-O-D-glucopyranoside) is a new compound. Dimethyl 4, 4′-dimethoxy-5, 6, 5′, 6′-dimethylenedioxybiphyenyl-2, 2'-dicarboxylate is a known synthetic compound, but it was first isolated from natural resource Astragalus root and identified by the authors.

关 键 词：蒙古黄芪 α-联苯双酯 黄芪异黄烷甙 

分 类 号：R284.1[医药卫生—中药学]