AECOPD痰培养及药敏分析  

Sputum cultivation and sensitivity tests for acute exacerbation chronic obstructive pulmonary disease

作　　者：卢家胜 李乔[1] 赵卫星[1] 

机构地区：[1]太和县中医院,安徽太和236600

出　　处：《中外医学研究》2011年第29期69-70,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的通过对笔者所在医院AECOPD患者痰培养及药敏结果进行统计分析,了解笔者所在医院目前主要耐药菌。方法对笔者所在医院近期具有完整细菌学资料的COPD患者痰培养及药敏结果进行分析。结果 682例患者痰培养中分离出病原菌252株,革兰氏阴性菌220株,占87.3%,主要为铜绿假单胞菌、大肠埃希菌、克雷伯杆菌、不动杆菌等,革兰氏阳性菌以金黄色葡萄球菌为主。药敏分析:革兰氏阴性杆菌对临床常见抗菌药物的耐药性,以阿莫西林耐药率最高,大部分革兰氏阴性菌对亚胺培南有较高敏感性。结论临床AECOPD呼吸道感染以革兰氏阴性菌为主,COPD病原菌对多种抗菌药物的耐药率有上升趋势,严格抗生素使用的管理,依据病原学检查机药敏试验结果合理使用,同时还需要严格控制使用疗程。Objective To provide the basis for rational application of antibiotics for the treatment of COPD by analyzing chronic obstructive pulmonary disease patients with sputum culture and sensitivity results.Methods The data was analyzed in our hospital of COPD patients with bacteriological Sputum culture and sensitivity test results.Results 682 cases of patients with sputum samples of 252 pathogens were isolated,gram-negative bacilli of 220,accounting for 87.3%,mainly pseudomonas aeruginosa,escherichia coli,klebsiella,acinetobacter and so on.In the gram-positive,the bacteria staphylococcus aureus more.Drug sensitive analysis,Gram-Negative bacillus had the highest drug fast rate to amoxicillin in all antibacterials which were usually used in clinic.Most Gram-Negative bacillus have hypersensitivity to Imipenem.Conclusion Most AECOPD patients were infected with Gram-Negative bacillus,COPD patients have a wide range of pathogens antimicrobial resistance which is on the rise.So we must to manage antibiotics which are used in clinical and reasonable adoption them according to aetiology test and susceptibility test and to control abusage with antibiotics.

关 键 词：慢性阻塞性肺疾病 痰培养 药敏试验 耐药率 

分 类 号：R446.5[医药卫生—诊断学]