珠海市49株肺炎链球菌耐药调查分析  

Susceptibility of 49 streptococcus pneumoniae in Zhuhai

作　　者：孟晓军[1] 孔红娟[1] 

机构地区：[1]中山大学附属第五医院,广东珠海519000

出　　处：《中外医学研究》2011年第29期71-72,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的调查分析2010年1月～12月临床分离肺炎链球菌的耐药情况,为临床用药提供参考。方法应用回顾性调查分析方法,对笔者所在医院2010年1～12月临床分离肺炎链球菌用全自动生化及药敏鉴定分析仪测定SP的抗生素敏感性。结果所有菌株对盖替沙星、莫西沙星、力奈唑烷、万古霉素、利福平敏感;而大部分菌株对青霉素G、四环素、复方新诺明和红霉素耐药,耐药率高,其中四环素耐药率最高,为96.0%,其他依次为红霉素(91.8%)、复方新诺明(71.6%)和青霉素G(57.1%),有多重耐药现象。结论 SP菌株对大环内酯类、磺胺类、青霉素类药物耐药情况严重,在临床和预防用药时,应慎重使用。加强肺炎链球菌的耐药监测对指导临床用药有十分重要的临床意义。Objective To analyze the drug-resistance of the strains of Streptococcus pneumoniae isolated during January to December 2010 to provide basis for clinical medication.Methods The retrospective analysis was conducted on the drugresistance of the strains of Streptococcus pneumoniae isolated during this period with VITEK 2-Compact.Results All 49 SP were sensitive to Gatifloxacin,Moxifloxacin,Linezolid,Vancomycin,Rifampicin;Drug resistance were high to Benzylpencillin,Trimethoprim,Erythromycin,Tetracycline.Conclusion The SP status showed widely resistant to Macrolides,sulfanilamide and Benzylpencillin which should be cautiously used in prophylaxis and therapy.Intensified the surveillance of the drug-resistance of the Streptococcus pneumoniae strains is essential to guide the clinical medication.

关 键 词：肺炎链球菌 抗生素敏感性 

分 类 号：R446.5[医药卫生—诊断学]