宫颈解脲支原体的分群分型检测与致病性研究  

Pathogenic research and classification points type testing of cervical M.urealyticum

作　　者：郑薇[1] 向梅[1] 韩秀玲[1] 刘玉梅[2] 

机构地区：[1]吉林大学第二医院妇产科,130041 [2]抚松县人民医院妇产科,134500

出　　处：《中国误诊学杂志》2011年第29期7067-7069,共3页Chinese Journal of Misdiagnostics

基　　金：吉林省科技发展计划项目(20030538-1)

摘　　要：目的探讨有阴道脓性分泌物症状的患者与正常对照组感染解脲支原体(UU)的生物种群及血清分型的差异,从而为临床合理治疗提供依据。方法用液体选择培养基初筛体检人群及门诊就诊患者319例,提取DNA,用PCR法进行分群分型。结果 231例有阴道脓性分泌物症状的患者中UU阳性率为34.6%(80例),对照组为29.5%(26例),二者之间差异无统计学意义(P>0.05)。观察组Ⅱ群阳性率47.5%明显高于正常对照组23.1%(P<0.05),而对照组Ⅰ群阳性率76.9%明显高于观察组52.5%(P<0.05)。观察组较对照组1型感染率有增高趋势。3、6、14型Uu感染率相近。结论有症状组与正常对照组Uu感染率相近,生物Ⅱ群与致病相关,临床应进一步进行Uu分群的检测。Objective To research the differences of biovars and serotypes between person who suffered from vaginal purulent secretion and the person who was not,which had great potential to detect it reasonably.Methods To choose 319 outpatients and healthy check-up people,Abstract DNA,grope and serotype with PCR.Results The positive rate of 231 cases patients who had symptom of vaginal purulent secretion was 34.6%,the rate of control group was 29.5%,and there was not statistical difference between them.The observ ation group＇s positive rate of（47.5%） was higher than control group（23.1%）,whereas the control group＇s positive rate of（76.9%） was higher than observation group（52.5%）.The observation group than controls had higher rates of type 1.The infection rate had no difference between 3,6 and 14 types.Conclutions The infection rate of observation group and control group have no difference between them,group were related to pathogenic,we should detected the biovars of UU.

关 键 词：解脲支原体/致病力/分类 

分 类 号：R375[医药卫生—病原生物学]