左氧氟沙星致中枢神经系统不良反应1例—-TypeA和TypeB足够吗？  

Case Analysis： Levofloxacin-related CNS Adverse Reactions-Are Type A and Type B Classification really enough？

作　　者：张久星[1] 刘娟[1] 刘高峰[1] 

机构地区：[1]哈尔滨医科大学附属第二医院药学部,黑龙江哈尔滨150086

出　　处：《药品评价》2011年第18期28-28,30-32,共4页Drug Evaluation

摘　　要：“经典”AB型分类方法是现在我国广泛使用的药品不良反应分类方法之一，但其定义相对宽泛，针对临床实际问题．不能一一做出详尽的解释。而DoTS、EIDOS以及EIDOS／DoTS分类方法的相继出现弥补了“经典”AB型分类方法的缺陷。本文通过对临床1例左氧氟沙星致中枢神经系统不良反应进行分析，对几种不良反应分类方法进行了比较，得出结论为EIDOS／DoTS分类方法几乎涵盖了药品不良反应的所有重要方面．随医学的发展，应用前景更为广阔。＂Classic＂ A/B type is now one of the widely used ADR classifications, however, its definition is relatively obscure, and can not make detailed explanation to guide clinical practice. DOTS, EIDOS and EIDOS/ DoTS classification methods have emerged subsequently to make up for the defects of the ＂classic＂ A/B type classification. In this paper, through the analysis of one case of levofloxacin caused adverse reactions to the central nervous system, the above classifications were compared. It is concluded that the EIDOS/DoTS classification can cover almost all important aspects of ADR and might be more prevalent with the development of medicine in the future.

关 键 词：左氧氟沙星 中枢神经系统不良反应 DoTS:EIDOS 

分 类 号：R969[医药卫生—药理学]