扩散张量成像及纤维束示踪成像观察正常脊髓  

Diffusion tensor imaging and tractography of normal spinal cord

作　　者：王葳[1] 秦文[2] 李坤成[3] 郝楠馨[1] 王轶彬[1] 宗根林[1] 杜育杉[1] 曹开明[1] 

机构地区：[1]同济大学附属东方医院医学影像科,上海200120 [2]天津医科大学总医院放射科,天津300052 [3]首都医科大学宣武医院放射科,北京100053

出　　处：《中国医学影像技术》2011年第10期1981-1984,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然基金重点项目(30930029);上海市卫生局基金项目(2008194)

摘　　要：目的探讨3.0T MR DTI及脊髓扩散张量纤维束示踪成像(DTT)技术的可行性及临床应用价值。方法应用3.0T MR成像系统对49名健康志愿者行脊髓DTI。分别测量颈髓、下段胸髓的ADC和FA值,同时进行各段脊髓DTT研究。采用单因素方差分析进行统计学分析。结果在颈髓与下段胸髓之间ADC和FA值差异均无统计学意义(P=0.745、0.196)。在DTT彩色编码图上,正常脊髓纤维束显示为头尾向的一束,存在头尾侧各向异性。结论脊髓DTI是描述扩散特征并直观显示脊髓纤维束的有效检查技术,可为脊髓病变提供扩散定量值参考。Objective To observe the feasibility and clinical values of DTI and tractography（DTT） of spinal cord.Methods Spinal cord DTI of 49 normal subjects were obtained on a 3.0T MR scanner.ADC and FA values were measured on the cervical and lower thoracic cord.The tracts were visualized.One way ANOVA was used to test the differences among spinal segments.Results There was no statistical difference among segments of cervical and lower thoracic cord（P=0.745,0.196）.On DTT maps,the normal spinal cord was depicted as a fiber tract showing color-encoded cephalocaudally.Conclusion DTI is a robust method for demonstrating the fiber tracts of the spinal cord and its diffusion characteristics,which can provided references of diffusion values for the spinal cord conditions.

关 键 词：扩散张量成像 脊髓 

分 类 号：R338.21[医药卫生—人体生理学] R445.2[医药卫生—基础医学]