慢性阻塞性肺疾病营养状况与甲状腺激素水平的关系  

Study on the correlation between nutrition status and thyroid hormone in patients with chronic obstructive pulmonary disease

作　　者：沈宏韬[1] 顾雪峰[1] 

机构地区：[1]安徽省蚌埠市第一人民医院呼吸内科,233000

出　　处：《蚌埠医学院学报》2011年第10期1081-1083,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨慢性阻塞性肺疾病(COPD)患者营养状况与甲状腺激素水平的关系。方法:COPD临床稳定期患者148例和健康对照组30名,根据体重指数(BMI)、理想体重百分比(NW%)、三头肌皮皱厚度(TSF)、上臂中点臂围(MAC)、血清白蛋白(ALB)、总淋巴细胞(LYM)等营养参数,将COPD患者分为COPD营养不良组(COPDⅠ组)47例和COPD非营养不良组(COPDⅡ组)101例。采用放射免疫法检测甲状腺激素,并探讨相互之间的相关关系。结果:COPDⅠ组BMI、NW%、TSF、MAC、ALB、LYM、T3、T4均低于COPDⅡ组、对照组(P<0.01),除对照组T4高于COPDⅡ组外,其余2组各指标差异均无统计学意义(P>0.05);所有营养参数与T3均呈正相关关系(P<0.05～P<0.01),ALB仅与T4呈正相关关系(P<0.05)。结论:甲状腺激素水平与COPD患者营养状况密切相关。Objective：To investigate the correlation between nutrition status and thyroid hormone in the patients with chronic obstructive pulmonary disease（COPD）.Methods：One hundred and forty-eight COPD patients in stable stage and 30 normal controls were studied.Nutritional parameters,including body mass index（BMI）,percentage of normal body mass（NM%）,triceps skin-fold thickness（TSF）,mid-upper arm circumference（MAC）,serum albumin（ALB）,and total lymphocyte counts（LYM） were determined.COPD patients were divided into malnutrition group（groupⅠ,47 cases） and non-malnutrition group（group Ⅱ,101 cases） according to these nutritional parameters.Thyroid hormones（including T3,T4 and TSH） were detected by radioimmunoassay method.The correlation between these parameters were analyzed.Results：In contrast to control group and groupⅡ,there were significant differences on BMI,NW%,TSF,MAC,ALB,LYM,T3 and T4 in group Ⅰ（P0.01）.Except that T4 in control group was higher than group Ⅱ,there were no significant difference on these parameters between the two groups（P0.05）.Significant correlation was existed between T3 and all nutritional parameters（P0.05-P0.01）,T4 was only linked to albumin（P0.05）.Conclusions：There is significant correlation between thyronine and nutritional status in patients with COPD.

关 键 词：肺疾病 慢性阻塞性 营养状况 甲状腺激素 相关性 

分 类 号：R563.9[医药卫生—呼吸系统]