牛结节性皮肤病及其病原检测方法研究进展  

Progress on Lumpy Skin Disease and Detection Metheds of Its Pathogen

作　　者：周雪梅[1,2] 李应国[2,3] 聂奎[1] 聂福平[2,3] 王昱[2,3] 肖进文[2,3] 

机构地区：[1]西南大学动物科技学院,重庆400715 [2]重庆出入境检验检疫局,重庆400020 [3]重庆进出口食品安全工程中心,重庆400020

出　　处：《动物医学进展》2011年第10期99-102,共4页Progress In Veterinary Medicine

摘　　要：牛结节性皮肤病(LSD)是由牛结节性皮肤病病毒(LSDV)引起的一种传染病。该病起源于非洲,在撒哈拉和马达加斯加呈地方流行,欧美国家鲜有发生,我国境内尚无牛结节性皮肤病。在疫病流行的非洲等地区和国家,该病的检测技术主要有病原分离鉴定、常规血清学检测和分子生物学检测。对于没有该病发生的地区和国家,有学者应用有交叉反应的同属的山羊痘病毒构建重组表达蛋白P32,建立间接ELISA方法进行检测。由于技术壁垒的原因,我国尚无该病检测的成熟技术。论文综述了该病近年来的发生发展情况,并对该病及其病原检测方法进行详细综述,为我国研究牛结节性皮肤病和建立快速检测方法提供依据。Lumpy skin disease（LSD） is caused by lumpy skin disease virus（LSDV）.It is endemic in most parts of sub-Saharan Africa and Madagascar.It rarely occurred in Europe and United States.There is no report of disease in China by now.In Africa,samples were usually detected by identification of the pathogen,serological tests and molecular biology.For the area without LSDV,an antibody ELISA based on the major antigen P32 were performed,btandard operation procedures were not performed in China becasuse of technical barriers.The etiological method,serological method and molecular biological method both at home and abroad,tfor LSDV detections were summarized.

关 键 词：牛结节性皮肤病 病原学 流行病学 检测方法 

分 类 号：S854.43[农业科学—临床兽医学]