生物监测暴露评价研究进展  

Research Progresses in Biomonitoring for Human Exposure Assessment

作　　者：仇付国[1] 高始涛[1] 陈顷[1] 

机构地区：[1]北京建筑工程学院城市雨水系统与水环境省部共建教育部重点实验室,北京100044

出　　处：《环境与健康杂志》2011年第10期933-936,共4页Journal of Environment and Health

基　　金：北京市属高等学校人才强教计划资助项目-中青年骨干人才资助项目(PHR201108199)

摘　　要：暴露评价作为健康风险评价技术的关键环节,近年来取得了显著进展。特别是生物监测技术的发展提供了大量的人体生物监测数据,为了直接利用生物监测数据评估人体健康风险,生物监测等效值的概念被提出并得到快速发展,建立了推导计算生物监测等效值的模型和方法,获得了大量化学物质的生物监测等效值。同时利用生物监测数据反向重建人体对环境污染物的暴露情况也有很大发展,这些研究将更加准确计算用于风险评价的暴露参数。该文对暴露评价在生物监测技术方面的最新进展进行了阐述。As a key step of health risk assessment processes, the exposure assessment has gained significant development in recent years, the development of biological monitoring technique had gained a mass of human monitoring data, in order to interpret the biomonitoring data in the health risk context, the concept of biomonitoring equivalents （BE） was recently developed and used to evaluate the human health risk by comparing the measured level and the BE value. In parallel with BE, much progress has been made also in reconstructing population exposures from dose biomarker. Precise human exposure parameters can be obtained from the biomonitoring data. This paper discussed the progress of biological monitoring techniques in exposure assessment.

关 键 词：暴露评价 生物监测 生物监测等效值 

分 类 号：R181.3[医药卫生—流行病学]