高血压患者血压昼夜模式与心率变异性的相关性分析  

Relation between abnormalities in blood pressure rhythm and heart rate variability

作　　者：刘丹[1] 王星[1] 苏晨[1] 陈艺莉[1] 黄慧玲[1] 

机构地区：[1]中山大学附属第一医院心内科,广州510080

出　　处：《中国实用内科杂志》2011年第10期787-788,共2页Chinese Journal of Practical Internal Medicine

摘　　要：目的探讨正常血压人群以及高血压人群中不同血压昼夜模式与心率变异性(HRV)的相关性分析。方法共入选2009年1月至2010年8月中山大学附属第一医院门诊及病房患者406例,其中高血压病例286例,根据动态血压监测结果分为杓型组、非杓型组和反杓型组,并设对照组120例。全部病例均在监测动态血压的同时记录动态心电图,并分析心率变异性的时域指标。结果非杓型组和反杓型组的SDNN、SDANN、SDNN index、RMSSD、pNN50和Triangular Index值均比杓型组和对照组降低(P<0.05),其中,反杓型组的上述指标明显降低。结论不同血压昼夜模式的高血压病患者HRV指标有明显差别,血压昼夜模式消失的高血压病患者自主神经功能受损更加严重。Objective To determine the relation between abnormalities in blood pressure rhythm and heart rate variability in individuals with hypertension. Methods The 24-hour ambulatory BP monitoring （ABPM） were performed in 100 dipper, 120 non-dipper,66 reverse-dipper hypertensive subjects and 120 control subjects. All the subjects underwent 24-hour Holter monitoring （Holter） to obtain heart rate variability （HRV） parameters of 24- hour. Results SDNN, SDANN, SDNN index, RMSSD, pNN50 and TriangUlar Index were significantly lower in non-dipper and reverse-dipper group than dipper group and controls （ P 〈 0. 05 ）., especially in reverse-dipper group. Conclusion HRV parameters decreased in the subjects without normal diurnal rhythm of the BP, suggesting the dysfunction of autonomic nervous system, especially in the reverse-dipper hypertension patients.

关 键 词：自主神经系统 高血压病 心率变异性 动态心电图 动态血压 

分 类 号：R544.1[医药卫生—心血管疾病]