血栓性微血管病发病机制及分类新认识  

Pathogenesis and classification of thrombotic microangiopathy:recent updates

作　　者：林宛兵[1] 陈楠[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院肾脏科,上海200025

出　　处：《中国实用内科杂志》2011年第10期799-801,共3页Chinese Journal of Practical Internal Medicine

摘　　要：血栓性微血管病(TMA)分血栓性血小板减少性紫癜及溶血尿毒症综合征(HUS),HUS又分感染后HUS和非典型HUS,现认为HUS发病主要与补体旁路途径的过度激活相关。Thrombocytopenic purpura （TTP） and hemolytic uremic syndrome （HUS） were distinguished from each other by whether with ADAMTS13 deficiency. Furthermore, hemolytic uremic syndrome （HUS） is sub- divided into postnfection HUS and atypical HUS. Currently,it is considered that the occurrence of HUS is related with excessive activation of the complement alternative pathway.

关 键 词：血栓性微血管病 血栓性血小板减少性紫癜 溶血尿毒症综合征 

分 类 号：R543[医药卫生—心血管疾病]