病毒性肝炎合并糖尿病预后与病毒因素的关系分析  

Connection of virologic factors and prognosis of viral hepatitis with diabetes

作　　者：刘大凤[1] 李亚玲[1] 李波[1] 沈柳漪[1] 刘纯芳[1] 王林[1] 胡蓉[1] 王丽[1] 张鸿[1] 

机构地区：[1]成都市传染病医院,四川成都610061

出　　处：《成都医学院学报》2011年第3期244-247,共4页Journal of Chengdu Medical College

基　　金：四川省卫生厅项目(项目编号:070385);成都市卫生局青年基金项目(项目编号:局0715)

摘　　要：目的探讨糖尿病对病毒性肝炎疾病预后的影响。方法回顾性分析住院的502例病毒性肝炎合并糖尿病及的病毒因素与预后的关系。结果 1)502例病毒性肝炎合并糖尿病患者好转所占比例最高(76.89%),其次是痊愈(14.34%),总体预后良好。2)分性别预后情况与总体预后一致,男女组间预后情况比较无统计学意义(P=0.333)。3)年龄<20岁组和年龄>80岁组100%好转;另三组好转率(约75%)及痊愈率相近(约14%),20～40岁组死亡率最低(2.50%);60～80岁组死亡率最高(7.44%)。各年龄段组间预后比较无统计学意义(P=0.130)。4)急性肝炎组预后最好;慢性肝炎组、肝硬化组、重型肝炎组,痊愈率逐渐下降,未愈和死亡逐渐增多,尤其是重型肝炎组预后最差。不同临床类型组间预后比较有统计学意义(P=0.000)。5)随着并发症个数的增加,痊愈率逐渐下降,未愈率及死亡率逐渐增加。不同并发症个数组间预后比较有统计学意义(P=0.000)。6)甲型肝炎组预后最好;重叠感染组、乙型肝炎组预后差。不同病毒型别组间预后比较有统计学意义(P=0.000)。结论病毒性肝炎合并糖尿病者总体预后良好。乙型和重叠感染的重型肝炎及肝硬化患者预后差一些,并发症个数越多预后越差,性别和年龄对疾病预后无明显影响。Objective To investigate the connection of virologic factors and prognosis of viral hepatitis with diabetes.Methods The virologic factors and its relationship with prognosis of 502 patients of viral hepatitis with diabetes were retrospectively analyzed.Results 1） Among the patients,14.34% were recovered and 76.89% were improved.2） The prognosis distribution of male group was similar with that of female group and total group.There was no significant deference in prognosis distribution between male group and female group（P=0.333）.3） Age bellow 20 years old group and age above 80 years old group had the highest ratio of being in effect（100.00%）.Not only ratio of recovery but also being in effect in other three group were similar each other.The lowest ratio of death was in age from 20 to 40 years old group.While The highest ratio of death was in age from 60 to 80 years old group.There was no significant deference in prognosis distribution between dissimilar age groups（P=0.130）.4） The acute hepatitis group had the best prognosis.Followed was chronic hepatitis group and cirrhosis group.Severe hepatitis group had the worst prognosis.There was significant deference in prognosis distribution between dissimilar clinical type groups（P=0.000）.5） The prognosis was from bad to worst together with the number of complications increasing.There was significant deference in prognosis distribution between dissimilar count of complication groups（P=0.000）.6） The hepatitis A group had the best prognosis.Followed were hepatitis C group,hepatitis D group and hepatitis E group.The hepatitis germination viral group had bad prognosis.The hepatitis B group had the worst prognosis.There was significant deference in prognosis distribution between dissimilar viral type groups（P=0.000）.Conclusions The prognosis of patients of viral hepatitis with diabetes was good.Severe hepatitis and cirrhosis patients with hepatitis B virus and germination virus infection had bad prognosis.The prognosis was from bad to worst

关 键 词：病毒因素 病毒性肝炎合并糖尿病 预后 

分 类 号：R473.5[医药卫生—护理学]