紫外分光光度法测定苯酚滴耳液的含量  

Determination of Phenol Concentration in Phenol Ear Drops by Ultraviolet Spectrophotometry

作　　者：潘萍[1] 

机构地区：[1]江苏省镇江市第四人民医院药剂科,江苏镇江212001

出　　处：《临床医学工程》2011年第10期1527-1528,共2页Clinical Medicine & Engineering

摘　　要：目的探讨苯酚滴耳液中苯酚含量测定方法。方法采用紫外分光光度法测定苯酚甘油滴耳液中苯酚含量,测定波长(270±1)nm。结果苯酚浓度在10～30mg/L浓度范围内线性关系良好,辅料对苯酚的测定无干扰。5组样品测定结果平均回收率99.81%,相对标准偏差(RSD)为0.57%。结论本方法操作简便,可用于该制剂的快速含量测定。Objective To establish a simple method for the detection of phenol concentration in phenol ear drops. Methods The ultraviolet spectrophotography was used, the detection wavelength was （270 ± 1） nm. Results The linearity was obtained in the range of 10 ~ 30 mg/L （r = 0.9999）. The average recovery was 99.81% in five group samples. The RSD was 0.57%. Conclusion The method is simple with high recovery and suitable for quick measurement in pharmacy.

关 键 词：苯酚滴耳液 含量测定 紫外分光光度法 

分 类 号：R927.2[医药卫生—药学]