偏氯含氟菊酯异构体的合成及其杀虫活性  

Syntheses of the Isomers of α-Cyano-4-fluoro-3-phenoxybenzyl Ester of Monochlorinated Pyrethric Acid and Their Insecticidal Activity

作　　者：郑祖彪[1] 李新军[1] 王翠翠[1] 邹新琢[1] 

机构地区：[1]华东师范大学化学系,上海200062

出　　处：《有机化学》2011年第10期1624-1630,共7页Chinese Journal of Organic Chemistry

基　　金：上海市科委资助重点(No.073919106)资助项目

摘　　要：α-氰基-4-氟-3-苯氧苄基-2,2-二甲基-3-(-2-氯乙烯基)-环丙烷羧酸酯(简称偏氯含氟菊酯)是一类新型拟除虫菊酯.报道了它的12个异构体的合成.生物活性测试结果表明,这些异构体对淡色库蚊四龄孑孓都显示出杀虫活性,其中(αS,1R,3R)-cis-E-异构体5aes和(αS,1R,3R)-cis-Z-异构体5azs显示出比溴氰菊酯更高的杀虫活性.α-Cyano-4-fluoro-3-phenoxybenzyl ester of monochlorinated pyrethric acid is a new kind of py-rethroids.Syntheses of the isomers of cis/trans-monochlorinated pyrethric acids and their esters were re-ported.The results of biological test indicated that these isomers of pyrethroids had insecticidal activities against Culex pipiens pallens（larvae）.And some of the isomers,such as（αS,1R,3R）-cis-E-isomer 5aes and（αS,1R,3R）-cis-Z-isomer 5azs,exhibit higher insecticidal activities than deltamethrin.

关 键 词：偏氯含氟菊酯 异构体 合成 拟除虫菊酯 杀虫活性 

分 类 号：TQ450.1[化学工程—农药化工]