人类微小病毒B19感染的最新进展  

Recent Research Progress in Human Parvovirus B19 Infection

作　　者：邵惠训[1] 

机构地区：[1]北京实验动物研究中心,北京100012

出　　处：《医学综述》2011年第20期3063-3066,共4页Medical Recapitulate

摘　　要：人类微小病毒B19主要侵袭人体骨髓造血系统,损害人体多种脏器,是儿科出疹性疾病——传染性红斑的病原。还可使慢性溶血患者发生再障危象、关节病、血管性紫癜和雷诺肢端综合征等。在免疫缺陷患者,可造成持续感染。妊娠期受到病毒侵害,引发宫内感染,可导致流产、胎儿水肿和死胎。此外,还与多种造血系统异常(中性粒细胞减少症和血小板减少症等)有关。Human parvovirus B19（HPV B19）,which mainly invades human hematopoietic system,damaging multiple human organs,is the pathogen of pediatric rash illness-infectious erythema.It may also cause aplastic crisis,arthropathy,vascular purpura,and Raynaud acromegaly syndrome of the patients with chronic hemolytic,and continuous infection in the immunocompromised patients.Abortion,fetal hydrops and stillbirth are complications of intrauterine HPV B19 infection.Besides,it′s also related with a variety of hematopoietic system abnormalities（neutropenia and thrombocytopenia）.

关 键 词：人类微小病毒B19 传染性红斑 红细胞再生障碍性贫血危象 血管性紫癜 胎内感染 

分 类 号：R373.9[医药卫生—病原生物学]