保留BMP的微脱矿骨条在脊柱融合术中的应用研究  

Clinical research of demineralized bone with BMP in spinal fusion

作　　者：张爱明[1] 李青[1] 蔡林[2] 袁元杏[1] 梁道臣[1] 梅治[1] 赵成毅[1] 

机构地区：[1]中山市人民医院脊柱外科,广东中山528403 [2]武汉大学中南医院骨科,湖北武汉430071

出　　处：《生物骨科材料与临床研究》2011年第5期23-25,共3页Orthopaedic Biomechanics Materials and Clinical Study

基　　金：中山市卫生局科研项目;2006016

摘　　要：目的探讨保留BMP的微脱矿骨条在脊柱融合术中的临床疗效。方法自2005年6月~2010年12月应用保留BMP的微脱矿骨条行脊柱融合术26例﹙实验组﹚,其中颈椎8例,胸腰椎18例,术后对所有患者行切口愈合情况、异物反应及脊柱融合情况进行观察,对照组为同期应用普通同种异体骨条行脊柱后路融合术26例。结果实验组与对照组伤口均一期愈合,未发生感染。颈椎实验组、对照组均现脊柱融合;胸腰椎实验组坚强融合16例,可能融合2例,对照组坚强融合13例,可能融合5例。随访6~24月,平均15.2月,内固定系统无松动及断钉断棒。结论保留BMP的微脱矿骨条应用在脊柱融合术中,脊柱融合可,无排异、感染等并发症,临床疗效满意。Objective To study the efficacy of spinal fusion by demineralized bone with BMP. Methods From Jun 2005 to Dec 2010, 26 patients underwent spinal fusion ~ 8 cases of cervical, 18 cases of thoracolumbar ）by demineralized bone with BMP while the control group with allograft bone. The clinical efficacy were evaluated from primary incision healing 、 fusion status. Result All skin incision healed primarily with no infection, the 8 cases of cervical obtained satisfying fus- ion ; the 18 cases of thoracolumbar. In experimentmal group 16 cases with solid fusion and 2 with uncertain fusion while 13 with solid fusion and 5with uncertain fusion in control group. During 6 to 24 months ~ mean 15.2 months ） follow-up period, no screw looseness and no broken screw occurred. Conclusion Spinal fusion by demineralized bone with BMP has an advantage of satisfying fusion and no infection which can take good clinic effect

关 键 词：脊柱 融合 微脱矿 BMP 

分 类 号：R687.3[医药卫生—骨科学]