负载型铁催化剂的制备及其在2,4,6-三甲基苯甲酸合成中的应用  

PREPARATION OF SUPPORTED IRON CATALYSTS AND ITS APPLICATION IN SYNTHESIS OF 2,4,6-METHYLBENZOIC ACID

作　　者：李华 周鹏松 金曼 田晏 

机构地区：[1]中国石油锦州石化公司,锦州121001 [2]东北化工销售公司辽西分公司

出　　处：《石油炼制与化工》2011年第11期9-12,共4页Petroleum Processing and Petrochemicals

摘　　要：研究了负载型铁催化剂的制备方法以及催化剂制备条件对2,4,6-三甲基苯甲酸合成中间体-α氯代-2,4,6-三甲基苯乙酮产率的影响。结果表明,适宜的催化剂制备条件为:以Al2O3为载体,铁负载量20%,活化温度400℃。通过正交实验得到使用该催化剂的最适宜酰基化反应条件:均三甲苯和氯乙酰氯的摩尔比1∶2,反应时间4h,反应温度80℃,催化剂用量为均三甲苯质量的0.25%。在此条件下,-α氯代-2,4,6-三甲基苯乙酮的产率为81.8%。The preparation of supported iron catalysts for application in the synthesis of 2,4,6-meth- ylbenzoic acid was studied including factors influencing the catalyst preparation on the yield of a-chlor 1- （2, 4, 6 trimethylphenyl） 1-ethanone, which was a synthetic intermediate of 2, 4, 6-methylbenzoic acid. Test results showed that the optimum catalyst preparation conditions were using alumina support with an iron loaded amount of 20 % and activation at 400 ℃. The optimum acylation conditions for mesit- ylene over said catalyst were obtained by orthogonal experiments as follows： C9 H12/ClCH2COCl molar ratio of 0.5, a reaction on the mass of mesityl nyl）-l-ethanone reache temperature of 80 ℃ ,a reaction time of 4 h and a catalyst dosage of 0.25% （based ene）. Under such reaction conditions, the yield of a-chlor-1-（2,4,6-trimethylphe- d 81.8%.

关 键 词：负载型铁催化剂 均三甲苯2 4 6-三甲基苯甲酸 酰基化反应 α-氯代-2 4 6-三甲基苯乙酮 

分 类 号：TQ245.12[化学工程—有机化工]